Sulfur fluoride exchange

JA Homer, L Xu, N Kayambu, Q Zheng… - Nature Reviews …, 2023 - nature.com
Click chemistry is a conceptual strategy to rapidly synthesize and discover functional
molecules. Sulfur fluoride exchange (SuFEx) is a click reaction that has revolutionized …

Linkage chemistry of S (VI) fluorides

D Zeng, WP Deng, X Jiang - Chemistry–A European Journal, 2023 - Wiley Online Library
Sulfur (VI)‐fluoride exchange linkage as a next generation of click chemistry was introduced
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …

Enantioselective sulfur (VI) fluoride exchange reaction of iminosulfur oxydifluorides

Z Peng, S Sun, MM Zheng, Y Li, X Li, S Li, XS Xue… - Nature Chemistry, 2024 - nature.com
Linkage chemistry and functional molecules derived from the stereogenic sulfur (VI) centre
have important applications in organic synthesis, bioconjugation, drug discovery …

Robust covalent aptamer strategy enables sensitive detection and enhanced inhibition of SARS-CoV-2 proteins

D Wang, J Zhang, Z Huang, Y Yang, T Fu… - ACS Central …, 2023 - ACS Publications
Aptamer-based detection and therapy have made substantial progress with cost control and
easy modification. However, the conformation lability of an aptamer typically causes the …

Fluorosulfonylvinylation of Unactivated C(sp3)–H via Electron Donor–Acceptor Photoactivation

X Zhao, D Chen, S Zhu, J Luo, S Liao, B Zheng… - Organic …, 2023 - ACS Publications
An electron donor–acceptor (EDA) complex photoactivation strategy for radical
fluorosulfonylation is disclosed for the first time. Simply upon blue light irradiation, the FSO2 …

Mechanism‐Guided Design of Chain‐Growth Click Polymerization Based on a Thiol‐Michael Reaction

S Jiang, H Huang - Angewandte Chemie, 2023 - Wiley Online Library
The development of chain‐growth click polymerization is challenging yet desirable in
modern polymer chemistry. In this work, we reported a novel chain‐growth click …

C (sp 3)–H fluorosulfonylvinylation/aza-Michael addition approach to FSO 2-functionalized tetrahydropyridines

S Shi, X Zhao, D Chen, J Luo, S Liao… - Organic Chemistry …, 2023 - pubs.rsc.org
A novel cascade approach is presented for the synthesis of FSO2-functionalized
tetrahydropyridines from propargyl alcohols, FSO2Cl, and anilines. This strategy …

Synthesis of Degradable Polysulfamides via Sulfur (VI) Fluoride Exchange Click Polymerization of AB-Type Monomers

JW Wu, RW Kulow, MKJ Redding, AJ Fine… - ACS Polymers …, 2023 - ACS Publications
Polysulfamides are the− SO2–analogues of polyureas and form an intriguing family of
polymers containing hydrogen-bond donor and acceptor groups. However, unlike …

Machine learning-accelerated discovery of heat-resistant polysulfates for electrostatic energy storage

H Li, H Zheng, T Yue, Z **e, SP Yu, J Zhou, T Kapri… - Nature Energy, 2025 - nature.com
The development of heat-resistant dielectric polymers that withstand intense electric fields at
high temperatures is critical for electrification. Balancing thermal stability and electrical …

Sulfur-phenolate exchange as a fluorine-free approach to S (VI) exchange chemistry on sulfonyl moieties

AFJ van den Boom, M Subramaniam, H Zuilhof - Organic Letters, 2022 - ACS Publications
SuFEx chemistry has recently evolved as next-generation click chemistry. However, in most
SuFEx syntheses, additional reagents/catalysts and carefully controlled conditions are still …