Biomolecular condensates regulate transcription by dynamically compartmentalizing the
transcription machinery. Classic models of transcription regulation focus on the recruitment …

Innate immunity is essential for the host against pathogens, cancer, and autoimmunity. The
innate immune system encodes many sensor, adaptor, and effector proteins and relies on …

Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …

Little is known about the regulation and function of phase separation in craniofacial
developmental disorders. MSX1 mutations are associated with human cleft palate, the most …

The phenomenon of phase separation is quite common in cells, and it is involved in multiple
processes of life activities. However, the current research on the correlation between protein …

Cellular compartmentalization, achieved through membrane‐based compartments, is a
fundamental aspect of cell biology that contributes to the evolutionary success of cells. While …

Liquid‐liquid phase separation (LLPS), mediated by G‐quadruplexes (G4 s) and intrinsically
disordered proteins, particularly those containing RGG domains, plays a critical role in …

Over the last decade, the exploration of protein phase separation has gained significant
momentum, unfolding as a novel frontier in biological studies. It has revealed a wide array of …

The high concentration of crystallin proteins in the lens maintains transparency and clarity
via a high refractive index that ensures optical quality. The chaperone-like activity of …