Stimulus-controlled anion binding and transport by synthetic receptors

J de Jong, JE Bos, SJ Wezenberg - Chemical Reviews, 2023 - ACS Publications
Anionic species are omnipresent and involved in many important biological processes. A
large number of artificial anion receptors has therefore been developed. Some of these are …

[HTML][HTML] Applications of supramolecular anion recognition

N Busschaert, C Caltagirone, W Van Rossom… - Chemical …, 2015 - ACS Publications
The study of the complexation of anions, from its beginnings in the late 1960s and 1970s,(1-
3) has moved on from being an area solely of academic interest to a fundamental pillar of …

Redox-activated pro-chelators

E Tomat, T Chang, EA Akam - US Patent 11,504,346, 2022 - Google Patents
(2014) Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the
regulation of ER stress and the epithelial mesenchymal transition. BBA Rev. Cancer 1845 …

Anion receptor chemistry

PA Gale, ENW Howe, X Wu - Chem, 2016 - cell.com
Anion Receptor Chemistry: Chem Skip to Main Content Skip to Main Menu Advertisement
Chem This journal offers authors two options (open access or subscription) to publish …

Progress and prospects toward supramolecular bioactive ion transporters

A Mondal, M Ahmad, D Mondal… - Chemical …, 2023 - pubs.rsc.org
The majority of cellular physiological processes depend on natural ion channels, which are
pore-forming membrane-embedded proteins that let ions flow across the cell membranes …

Discovery and optimization of tambjamines as a novel class of antileishmanial agents

P Kancharla, D Ortiz, CM Fargo, X Zhang… - Journal of medicinal …, 2024 - ACS Publications
Leishmaniasis is a neglected tropical disease that is estimated to afflict over 12 million
people. Current drugs for leishmaniasis suffer from serious deficiencies, including toxicity …

[HTML][HTML] Tuning pH-dependent cytotoxicity in cancer cells by peripheral fluorine substitution on pseudopeptidic cages

L Tapia, Y Pérez, I Carreira-Barral, J Bujons… - Cell Reports Physical …, 2024 - cell.com
The acidic microenvironment of solid tumors is a potential source of selectivity in the anti-
cancer activity of ionophores, which requires delicate control of their biophysical properties …

Microorganisms in the treatment of cancer: advantages and limitations

K Łukasiewicz, M Fol - Journal of immunology research, 2018 - Wiley Online Library
Cancer remains one of the major challenges of the 21st century. The increasing numbers of
cases are not accompanied by adequate progress in therapy. The standard methods of …

pH-regulated nonelectrogenic anion transport by phenylthiosemicarbazones

ENW Howe, N Busschaert, X Wu… - Journal of the …, 2016 - ACS Publications
Gated ion transport across biological membranes is an intrinsic process regulated by protein
channels. Synthetic anion carriers (anionophores) have potential applications in biological …

Pyrrole N–H anion complexes

GI Vargas-Zúñiga, JL Sessler - Coordination chemistry reviews, 2017 - Elsevier
Synthetic pyrrole-based anion receptors date back to the 1990s. They have been
extensively developed in the context of macrocyclic systems such as expanded porphyrins …