A forward vision for chemodynamic therapy: issues and opportunities

P Zhao, H Li, W Bu - Angewandte Chemie International Edition, 2023 - Wiley Online Library
Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Formation and repair of oxidatively generated damage in cellular DNA

J Cadet, KJA Davies, MHG Medeiros… - Free Radical Biology …, 2017 - Elsevier
In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

Thermochemistry of proton-coupled electron transfer reagents and its implications

JJ Warren, TA Tronic, JM Mayer - Chemical reviews, 2010 - ACS Publications
Many, if not most, redox reactions are coupled to proton transfers. This includes most
common sources of chemical potential energy, from the bioenergetic processes that power …

Boronate oxidation as a bioorthogonal reaction approach for studying the chemistry of hydrogen peroxide in living systems

AR Lippert, GC Van de Bittner… - Accounts of chemical …, 2011 - ACS Publications
Reactive oxygen species (ROS), such as hydrogen peroxide, are important products of
oxygen metabolism that, when misregulated, can accumulate and cause oxidative stress …

Traumatic brain injury: oxidative stress and neuroprotection

C Cornelius, R Crupi, V Calabrese… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: A vast amount of circumstantial evidence implicates high energy oxidants and
oxidative stress as mediators of secondary damage associated with traumatic brain injury …

Electrochemistry of nucleic acids

E Palecek, M Bartosik - Chemical Reviews, 2012 - ACS Publications
Large differences between the DPP responses of ss-and dsDNAs (Figure 4B) suggest that
the double-helical structure of the dsDNA is not significantly disturbed at the DME surface …

Oxidatively generated base damage to cellular DNA

J Cadet, T Douki, JL Ravanat - Free Radical Biology and Medicine, 2010 - Elsevier
Search for the formation of oxidatively base damage in cellular DNA has been a matter of
debate for more than 40years due to the lack of accurate methods for the measurement of …

Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions

J Cadet, S Mouret, JL Ravanat… - Photochemistry and …, 2012 - Wiley Online Library
The survey focuses on recent aspects of photochemical reactions to cellular DNA that are
implicated through the predominant formation of mostly bipyrimidine photoproducts in …

Organelle targetable fluorescent probes for hydrogen peroxide

Y Wen, F Huo, C Yin - Chinese Chemical Letters, 2019 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2), as important products of oxygen metabolism, plays
an important role in many biological processes, such as immune responses and cellular …