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Modulating biomolecular condensates: a novel approach to drug discovery
In the past decade, membraneless assemblies known as biomolecular condensates have
been reported to play key roles in many cellular functions by compartmentalizing specific …
been reported to play key roles in many cellular functions by compartmentalizing specific …
Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
[HTML][HTML] Glioblastoma hijacks neuronal mechanisms for brain invasion
Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …
Cellpose3: one-click image restoration for improved cellular segmentation
Generalist methods for cellular segmentation have good out-of-the-box performance on a
variety of image types; however, existing methods struggle for images that are degraded by …
variety of image types; however, existing methods struggle for images that are degraded by …
Rationalized deep learning super-resolution microscopy for sustained live imaging of rapid subcellular processes
The goal when imaging bioprocesses with optical microscopy is to acquire the most
spatiotemporal information with the least invasiveness. Deep neural networks have …
spatiotemporal information with the least invasiveness. Deep neural networks have …
Light sheet fluorescence microscopy
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …
Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy
A main determinant of the spatial resolution of live-cell super-resolution (SR) microscopes is
the maximum photon flux that can be collected. To further increase the effective resolution …
the maximum photon flux that can be collected. To further increase the effective resolution …
Democratising deep learning for microscopy with ZeroCostDL4Mic
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …
outperform conventional image processing pipelines. Despite the enthusiasm and …
Vision Transformers in medical computer vision—A contemplative retrospection
Abstract Vision Transformers (ViTs), with the magnificent potential to unravel the information
contained within images, have evolved as one of the most contemporary and dominant …
contained within images, have evolved as one of the most contemporary and dominant …
Inference in artificial intelligence with deep optics and photonics
Artificial intelligence tasks across numerous applications require accelerators for fast and
low-power execution. Optical computing systems may be able to meet these domain-specific …
low-power execution. Optical computing systems may be able to meet these domain-specific …