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Design and application of fluorescent probes to detect cellular physical microenvironments
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …
subcellular compartments, living cells, and organisms. In particular, physical properties …
Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
Chemical approaches to optimize the properties of organic fluorophores for imaging and sensing
G Jiang, H Liu, H Liu, G Ke, TB Ren… - Angewandte …, 2024 - Wiley Online Library
Organic fluorophores are indispensable tools in cells, tissue and in vivo imaging, and have
enabled much progress in the wide range of biological and biomedical fields. However …
enabled much progress in the wide range of biological and biomedical fields. However …
Fluorescent nanoparticles for super-resolution imaging
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …
Hybrid small-molecule/protein fluorescent probes
M Minoshima, SI Reja, R Hashimoto, K Iijima… - Chemical …, 2024 - ACS Publications
Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …
localization and function in living cells. These hybrid probes are constructed by diverse site …
Super-resolution microscopy for structural cell biology
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
Capturing mitochondria's intricate and dynamic structure poses a daunting challenge for
optical nanoscopy. Different labeling strategies have been demonstrated for live-cell …
optical nanoscopy. Different labeling strategies have been demonstrated for live-cell …
Rational design of a highly selective near‐infrared two‐photon fluorogenic probe for imaging orthotopic hepatocellular carcinoma chemotherapy
Selective fluorescence imaging of biomarkers in vivo and in situ for evaluating orthotopic
hepatocellular carcinoma (HCC) chemotherapy remains a great challenge due to current …
hepatocellular carcinoma (HCC) chemotherapy remains a great challenge due to current …
Simultaneous two-color visualization of lipid droplets and endoplasmic reticulum and their interplay by single fluorescent probes in lambda mode
In living systems, subcellular organelles mutually cooperate and closely contact to form
organelle interaction networks. Thus, the simultaneous and discriminative visualization of …
organelle interaction networks. Thus, the simultaneous and discriminative visualization of …