An update on safety and side effects of cannabidiol: a review of clinical data and relevant animal studies
K Iffland, F Grotenhermen - Cannabis and cannabinoid research, 2017 - liebertpub.com
Introduction: This literature survey aims to extend the comprehensive survey performed by
Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from …
Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from …
The essential medicinal chemistry of cannabidiol (CBD)
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABAA receptors
T Bakas, PS Van Nieuwenhuijzen, SO Devenish… - Pharmacological …, 2017 - Elsevier
Cannabidiol (CBD) is a major non-intoxicating component of cannabis and possesses anti-
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …
Pharmacokinetics of phytocannabinoid acids and anticonvulsant effect of cannabidiolic acid in a mouse model of Dravet syndrome
LL Anderson, IK Low, SD Banister… - Journal of natural …, 2019 - ACS Publications
Cannabis sativa produces a complex mixture of many bioactive molecules including
terpenophenolic compounds known as phytocannabinoids. Phytocannabinoids come in …
terpenophenolic compounds known as phytocannabinoids. Phytocannabinoids come in …
Cannabinoids, blood–brain barrier, and brain disposition
F Calapai, L Cardia, EE Sorbara, M Navarra… - Pharmaceutics, 2020 - mdpi.com
Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and
cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory …
cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory …
Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations
LL Anderson, MG Etchart, D Bahceci… - Scientific reports, 2021 - nature.com
Cannabis is a complex mixture of hundreds of bioactive molecules. This provides the
potential for pharmacological interactions between cannabis constituents, a phenomenon …
potential for pharmacological interactions between cannabis constituents, a phenomenon …
Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
Modeling blood–brain barrier pathology in cerebrovascular disease in vitro: current and future paradigms
AV Andjelkovic, SM Stamatovic, CM Phillips… - Fluids and Barriers of …, 2020 - Springer
The complexity of the blood–brain barrier (BBB) and neurovascular unit (NVU) was and still
is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the …
is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the …
Oral delivery of cannabidiol: revealing the formulation and absorption challenges
Cannabidiol (CBD) is a pharmacologically active, non-psychoactive cannabinoid derived
from natural sources. Currently, it is available in prescription oral dosage forms for its anti …
from natural sources. Currently, it is available in prescription oral dosage forms for its anti …
A marijuana-drug interaction primer: precipitants, pharmacology, and pharmacokinetics
Abstract In the United States, the evolving landscape of state-legal marijuana use for
recreational and/or medical purposes has given rise to flourishing markets for marijuana and …
recreational and/or medical purposes has given rise to flourishing markets for marijuana and …