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Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules
Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …
pathogens. While their use declined with the discovery of new antibiotics, they are now …
Structural and Functional Analyses of STM14_5441-STM14_5442: A Potential Mechanism for Persister Formation Against Aminoglycosides
HJ Eun, SW Jang, JH Park, J Lee, KY Lee, EJ Lee… - Drug Resistance …, 2025 - Elsevier
Aims The ability to eliminate bacterial persister cells is still a medical challenge that has yet
to be overcome. These cells represent a unique subpopulation within bacterial communities …
to be overcome. These cells represent a unique subpopulation within bacterial communities …
RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae
E Krin, A Carvalho, M Lang, A Babosan… - Microbiology …, 2023 - journals.asm.org
RavA-ViaA were reported to play a role in aminoglycoside (AG) sensitivity, but the
mechanisms remain elusive. Here, we performed competition and survival experiments to …
mechanisms remain elusive. Here, we performed competition and survival experiments to …
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
M Lang, S Renard, I El-Meouche, A Amoura… - bioRxiv, 2023 - biorxiv.org
Aminoglycosides (AGs) are broad-spectrum antibiotics effective against Gram-negative
bacteria. AG uptake depends on membrane potential, but the precise mechanisms are …
bacteria. AG uptake depends on membrane potential, but the precise mechanisms are …