Fibroblast and myofibroblast activation in normal tissue repair and fibrosis

FS Younesi, AE Miller, TH Barker, FMV Rossi… - … Reviews Molecular Cell …, 2024 - nature.com
The term 'fibroblast'often serves as a catch-all for a diverse array of mesenchymal cells,
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …

The materials science of collagen

VR Sherman, W Yang, MA Meyers - Journal of the mechanical behavior of …, 2015 - Elsevier
Collagen is the principal biopolymer in the extracellular matrix of both vertebrates and
invertebrates. It is produced in specialized cells (fibroblasts) and extracted into the body by a …

Extracellular matrix determinants of proteolytic and non-proteolytic cell migration

K Wolf, P Friedl - Trends in cell biology, 2011 - cell.com
Cell invasion into the 3D extracellular matrix (ECM) is a multistep biophysical process
involved in inflammation, tissue repair, and metastatic cancer invasion. Migrating cells …

The role of mechanical loading in tendon development, maintenance, injury, and repair

MT Galloway, AL Lalley, JT Shearn - JBJS, 2013 - journals.lww.com
The Role of Mechanical Loading in Tendon Development, Mainte... : JBJS The Role of
Mechanical Loading in Tendon Development, Maintenance, Injury, and Repair : JBJS JBJS …

Biomaterials in tendon and skeletal muscle tissue engineering: current trends and challenges

M Beldjilali-Labro, A Garcia Garcia, F Farhat, F Bedoui… - Materials, 2018 - mdpi.com
Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …

Mechanochemistry of collagen

SM Siadat, JW Ruberti - Acta Biomaterialia, 2023 - Elsevier
The collagen molecular family is the result of nearly one billion years of evolution. It is a
unique family of proteins, the majority of which provide general mechanical support to …

Mechanical homeostasis in tissue equivalents: a review

JF Eichinger, LJ Haeusel, D Paukner, RC Aydin… - … and modeling in …, 2021 - Springer
There is substantial evidence that growth and remodeling of load bearing soft biological
tissues is to a large extent controlled by mechanical factors. Mechanical homeostasis, which …

Mechanical strain stabilizes reconstituted collagen fibrils against enzymatic degradation by mammalian collagenase matrix metalloproteinase 8 (MMP-8)

BP Flynn, AP Bhole, N Saeidi, M Liles, CA DiMarzio… - PloS one, 2010 - journals.plos.org
Background Collagen, a triple-helical, self-organizing protein, is the predominant structural
protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin …

[HTML][HTML] Molecular biomechanics of collagen molecules

SW Chang, MJ Buehler - Materials Today, 2014 - Elsevier
Collagenous tissues, made of collagen molecules, such as tendon and bone, are intriguing
materials that have the ability to respond to mechanical forces by altering their structures …

Material properties of the posterior human sclera

R Grytz, MA Fazio, MJA Girard, V Libertiaux… - Journal of the …, 2014 - Elsevier
To characterize the material properties of posterior and peripapillary sclera from human
donors, and to investigate the macro-and micro-scale strains as potential control …