Genetic and epigenetic studies in diabetic kidney disease

HF Gu - Frontiers in genetics, 2019 - frontiersin.org
Chronic kidney disease is a worldwide health crisis, while diabetic kidney disease (DKD)
has become the leading cause of end-stage renal disease (ESRD). DKD is a microvascular …

Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population

I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Association of ELMO1 genetic polymorphism (rs741301) with the progression of diabetic kidney disease in Balinese patients with type 2 diabetes mellitus

AAIK Kirtaniya, A Lestarini… - Molecular and …, 2023 - cellbiopharm.com
Background: Diabetic kidney disease (DKD) is one of diabetes mellitus microvascular
complications. Engulfment and cell motility 1 (ELMO1) protein interacts with dedicator of …

Identification and characterization of differentially expressed genes in type 2 diabetes using in silico approach

MK Gupta, R Vadde - Computational Biology and Chemistry, 2019 - Elsevier
Diabetes mellitus is clinically characterized by hyperglycemia. Though many studies have
been done to understand the mechanism of Type 2 Diabetes (T2D), however, the complete …

[PDF][PDF] Expression Level of Circulating Cell Free miR-155 Gene in Serum of Patients with Diabetic Nephropathy.

M Akhbari, M Khalili, M Shahrabi-Farahani… - Clinical …, 2019 - researchgate.net
Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease
worldwide. Several factors are known to contribute to the development and progression of …

A meta-analysis and review on genetic map** of type 2 diabetes mellitus in Iraq

KNJ Musafer, M Rava, AS Chobok… - Egyptian Journal of …, 2023 - Springer
Background The prevalence of type 2 diabetes mellitus (T2DM) has been increasing rapidly
in Iraq over the past few decades. Identifying the most significant factors contributing to the …

WT1 and ACE mRNAs of blood extracellular vesicle as biomarkers of diabetic nephropathy

E Hashemi, H Dehghanbanadaki… - Journal of translational …, 2021 - Springer
Background Diabetic nephropathy (DN) has an increasing global prevalence with excessive
health expenditure and burden. Exosomal mRNAs regulate intercellular communications …

Association of ELMO1 gene polymorphism and diabetic nephropathy among Egyptian patients with type 2 diabetes mellitus

NMK Bayoumy, MM El‐Shabrawi… - Diabetes/metabolism …, 2020 - Wiley Online Library
Abstract Background and Objective Diabetic nephropathy (DN) is the most common cause of
end stage renal failure or even death among patients with type 2 diabetes mellitus. Genetic …

Expression of JAZF1, ABCC8, KCNJ11and Notch2 genes and vitamin D receptor polymorphisms in type 2 diabetes, and their association with microvascular …

MA Rasheed, N Kantoush… - Therapeutic …, 2017 - journals.sagepub.com
Background: We studied JAZF1, ABCC8, KCNJ11and Notch2 gene expression and vitamin
D receptor (VDR) polymorphisms (Fok1 and Bsm1) in patients with type 2 diabetes mellitus …

Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis

A Azarboo, S Hosseinkhani, A Ghaseminejad-Raeini… - Plos one, 2024 - journals.plos.org
Background Previous research has suggested that the ELMO1 gene may play a role in the
development of diabetic kidney disease. Diabetic kidney disease (DKD) is a serious …