Revisiting the thorny issue of missing values in single-cell proteomics
Missing values are a notable challenge when analyzing mass spectrometry-based
proteomics data. While the field is still actively debating the best practices, the challenge …
proteomics data. While the field is still actively debating the best practices, the challenge …
scCAN: single-cell clustering using autoencoder and network fusion
Unsupervised clustering of single-cell RNA sequencing data (scRNA-seq) is important
because it allows us to identify putative cell types. However, the large number of cells (up to …
because it allows us to identify putative cell types. However, the large number of cells (up to …
SAE-Impute: imputation for single-cell data via subspace regression and auto-encoders
L Bai, B Ji, S Wang - BMC bioinformatics, 2024 - Springer
Background Single-cell RNA sequencing (scRNA-seq) technology has emerged as a crucial
tool for studying cellular heterogeneity. However, dropouts are inherent to the sequencing …
tool for studying cellular heterogeneity. However, dropouts are inherent to the sequencing …
scGAA: a general gated axial-attention model for accurate cell-type annotation of single-cell RNA-seq data
T Kong, T Yu, J Zhao, Z Hu, N **ong, J Wan, X Dong… - Scientific Reports, 2024 - nature.com
Single-cell RNA sequencing (scRNA-seq) is a key technology for investigating cell
development and analysing cell diversity across various diseases. However, the high …
development and analysing cell diversity across various diseases. However, the high …
Inferring single-cell trajectories via critical cell identification using graph centrality algorithm
Trajectory inference (TI) aims to infer cell differentiation trajectories in biological processes.
Numerous computational methods have been developed to infer cell lineages from single …
Numerous computational methods have been developed to infer cell lineages from single …
Improved downstream functional analysis of single-cell RNA-sequence data using DGAN
The dramatic increase in the number of single-cell RNA-sequence (scRNA-seq)
investigations is indeed an endorsement of the new-fangled proficiencies of next generation …
investigations is indeed an endorsement of the new-fangled proficiencies of next generation …
Imputation method for dropout in single-cell transcriptome data
C Jiang, L Hu, C Xu, Q Ge, X Zhao - Sheng wu yi xue Gong Cheng …, 2023 - europepmc.org
单细胞转录组测序 (scRNA-seq) 可以在单细胞精度下解析组织中细胞的表达特征,
使得研究人员能以更高的分辨率定量群体内的细胞异质性, 揭示潜在的异质细胞群体和复杂组织 …
使得研究人员能以更高的分辨率定量群体内的细胞异质性, 揭示潜在的异质细胞群体和复杂组织 …
Imputation method for single-cell RNA-seq data using neural topic model
Y Qi, S Han, L Tang, L Liu - GigaScience, 2023 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) technology studies transcriptome and cell-to-cell
differences from higher single-cell resolution and different perspectives. Despite the …
differences from higher single-cell resolution and different perspectives. Despite the …
Dwen: A novel method for accurate estimation of cell type compositions from bulk data samples
Advances in single-cell RNA sequencing (scRNAseq) technologies have allowed us to
study the heterogeneity of cell populations. The cell compositions of tissues from different …
study the heterogeneity of cell populations. The cell compositions of tissues from different …
Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging
Multiplex tissue imaging are a collection of increasingly popular single-cell spatial
proteomics and transcriptomics assays for characterizing biological tissues both …
proteomics and transcriptomics assays for characterizing biological tissues both …