Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

[HTML][HTML] 3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Towards organoid culture without Matrigel

MT Kozlowski, CJ Crook, HT Ku - Communications biology, 2021 - nature.com
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

[HTML][HTML] Decellularized extracellular matrix biomaterials for regenerative therapies: advances, challenges and clinical prospects

AA Golebiowska, JT Intravaia, VM Sathe, SG Kumbar… - Bioactive Materials, 2024 - Elsevier
Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Biomedical applications of carbon nanomaterials: fullerenes, quantum dots, nanotubes, nanofibers, and graphene

M Gaur, C Misra, AB Yadav, S Swaroop… - Materials, 2021 - mdpi.com
Carbon nanomaterials (CNMs) have received tremendous interest in the area of
nanotechnology due to their unique properties and flexible dimensional structure. CNMs …

[HTML][HTML] Biofabrication methods for reconstructing extracellular matrix mimetics

A Aazmi, D Zhang, C Mazzaglia, M Yu, Z Wang… - Bioactive Materials, 2024 - Elsevier
In the human body, almost all cells interact with extracellular matrices (ECMs), which have
tissue and organ-specific compositions and architectures. These ECMs not only function as …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Reversed-engineered human alveolar lung-on-a-chip model

D Huang, T Liu, J Liao, S Maharjan, X **e… - Proceedings of the …, 2021 - pnas.org
Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made …