Abstract Alzheimer's disease (AD), the leading cause of dementia, is characterized by the
accumulation of amyloid plaques and neurofibrillary tangles in the brain. This condition …

Tau protein plays a pivotal role in the central nervous system (CNS), participating in
microtubule stability, axonal transport, and synaptic communication. Research interest has …

Caspases are a family of cysteine-dependent proteases with important cellular functions in
inflammation and apoptosis, while also implicated in human diseases. Classical chemical …

Tauopathies are neurodegenerative diseases that typically require postmortem examination
for a definitive diagnosis. Detecting neurotoxic tau fragments in cerebrospinal fluid (CSF) …

Background: Laminopathy is a pathological manifestation observed in Alzheimer's disease
(AD), leading to neuronal apoptosis. Objective: Our objective was to assess inhibitors of …

The consequence of chronic kidney disease is the accumulation of metabolic products
called uremic toxins in the body. Indoxyl sulfate (IS) is a toxin with a high affinity for proteins …

The prenylation of proteins is involved in a variety of biological functions. However, it
remains unknown whether it plays an important role in the morphogenesis of the …

This study aims to explore the expression profile of PANoptosis‐related genes (PRGs) and
immune infiltration in Alzheimer's disease (AD). Based on the Gene Expression Omnibus …

The caspases are a family of cysteine dependent proteases with important cellular functions
in inflammation and apoptosis, while also implicated in human disease. Classical chemical …

The consequence of chronic kidney disease is the accumulation of metabolic products
called uremic toxins in the body. Indoxyl sulfate (IS) is a toxin with a high affinity for proteins …