Depressive disorders are often accompanied by severe and pervasive impairments in social
functioning, surpassing those experienced by individuals with other chronic medical …

The current meta-analysis explored relationships between functional outcomes in
schizophrenia spectrum disorders and different domains of neurocognition and social …

Autism spectrum disorder (ASD) and schizophrenia (SCZ) are separate disorders, with
distinct clinical profiles and natural histories. ASD, typically diagnosed in childhood, is …

Importance It remains uncertain whether people with psychotic disorders experience
progressive cognitive decline or normal cognitive aging after first hospitalization. This …

Importance Schizophrenia is associated with major cognitive deficits and has been
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …

Objective The aim was to examine the general outcome of schizophrenia after 20 years or
more. Methods Using the PRISMA guidelines, we conducted a systematic review and meta …

Schizophrenia is a severe mental disorder with an unclear pathophysiology. Increased
expression of the immune gene C4 has been linked to a greater risk of develo** …

This study aimed to identify the 20‐year trajectories of positive and negative symptoms after
the first psychotic episode in a sample of patients with an ICD‐10 diagnosis of schizophrenia …

This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …

Understanding whether and how the schizophrenia polygenic risk score (SZ PRS) predicts
course of illness could improve diagnosis and prognostication in psychotic disorders. We …