[HTML][HTML] Regulation of de novo and maintenance DNA methylation by DNA methyltransferases in postimplantation embryos

Z Xu, J Shi, Q Chen, S Yang, Z Wang, B **ao… - Journal of Biological …, 2025 - Elsevier
DNA methylation is mainly catalyzed by three DNA methyltransferase (DNMT) proteins in
mammals. Usually DNMT1 is considered the primary DNMT for maintenance DNA …

The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor …

A Geethadevi, N Vaidya, RJ Fisher, T Findlay, Y Deng… - bioRxiv, 2024 - biorxiv.org
Background: Atypical teratoid rhabdoid tumor (ATRT) is the most common malignant brain
tumor in infants, and more than 60% of children with ATRT die from their tumor. ATRT is …

Long-range gene regulation and 3D organization of the glioblastoma genome

I Nissen - 2025 - diva-portal.org
Background: Glioblastoma (GB) is the most aggressive of all primary brain tumours and due
to its highly invasive nature, surgical resection is nearly impossible. Patients typically rely on …