Aggregation-induced emission: together we shine, united we soar!

J Mei, NLC Leung, RTK Kwok, JWY Lam… - Chemical …, 2015 - ACS Publications
Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …

Tumour acidosis: from the passenger to the driver's seat

C Corbet, O Feron - Nature Reviews Cancer, 2017 - nature.com
The high metabolic demand of cancer cells leads to an accumulation of H+ ions in the
tumour microenvironment. The disorganized tumour vasculature prevents an efficient wash …

Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

Gold nanoparticles as radiosensitizers in cancer radiotherapy

Y Chen, J Yang, S Fu, J Wu - International Journal of …, 2020 - Taylor & Francis
The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …

Diverse gatekeepers for mesoporous silica nanoparticle based drug delivery systems

J Wen, K Yang, F Liu, H Li, Y Xu, S Sun - Chemical Society Reviews, 2017 - pubs.rsc.org
Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug
delivery systems (DDSs) are developed as alternatives owing to their potential to selectively …

Targeting noncoding RNAs in disease

BD Adams, C Parsons, L Walker… - The Journal of …, 2017 - Am Soc Clin Investig
Many RNA species have been identified as important players in the development of chronic
diseases, including cancer. Over the past decade, numerous studies have highlighted how …

Surface-engineered dendrimers in gene delivery

J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake

Q **, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Stimuli-responsive nanoparticles for targeting the tumor microenvironment

J Du, LA Lane, S Nie - Journal of Controlled Release, 2015 - Elsevier
One of the most challenging and clinically important goals in nanomedicine is to deliver
imaging and therapeutic agents to solid tumors. Here we discuss the recent design and …

Gold nanoparticles as contrast agents in x-ray imaging and computed tomography

LE Cole, RD Ross, JMR Tilley, T Vargo-Gogola… - …, 2015 - Taylor & Francis
Computed tomography enables 3D anatomic imaging at a high spatial resolution, but
requires delivery of an x-ray contrast agent to distinguish tissues with similar or low x-ray …