Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome
of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million …

The hepatitis C virus (HCV) is a globally prevalent human pathogen that causes persistent
liver infections in most infected individuals. HCV is classified into seven phylogenetically …

Their extremely error-prone replication makes RNA viruses targets for lethal mutagenesis. In
the case of hepatitis C virus (HCV), the standard treatment includes ribavirin, a base analog …

The African swine fever virus (ASFV) has severely influenced the swine industry of the world.
Currently, there is no effective vaccine or drugs against the ASFV. How to effectively control …

Hepatitis C virus (HCV) is a major cause of liver disease worldwide and a potential cause of
substantial morbidity and mortality in the future. HCV is characterized by a high level of …

Single-cell genomics is emerging as an important tool in cellular biology. We describe for
the first time a system to investigate RNA virus quasispecies diversity at the cellular level …

Hepatitis C virus (HCV) is a major health problem worldwide, infecting an estimated 170
million people. The high genetic variability of HCV contributes to the chronicity of hepatitis C …

Pre-treatment HCV quasispecies complexity and diversity may predict response to interferon
based anti-viral therapy. The objective of this study was to retrospectively (1) examine …

The envelope 2 protein of hepatitis C virus (HCV) presents three hypervariable regions,
named HVR1, HVR2 and HVR3, in which the presence of antigenic sites has been …

Hepatitis C virus (HCV) exists as a quasispecies within an infected individual. We have
previously reported an in-frame 3 bp insertion event at the N-terminal region of the E2 …