Resurrecting enzymes by ancestral sequence reconstruction

ML Mascotti - Enzyme Engineering: Methods and Protocols, 2022 - Springer
Abstract Ancestral Sequence Reconstruction (ASR) allows one to infer the sequences of
extinct proteins using the phylogeny of extant proteins. It consists of disclosing the …

[BOOK][B] Codon evolution: mechanisms and models

GM Cannarozzi, A Schneider - 2012 - books.google.com
Codon-based models of evolution are a relatively new addition to the toolkit of
computational biologists, and in recent years remarkable progress has been made in this …

Surprising results on phylogenetic tree building methods based on molecular sequences

GH Gonnet - BMC bioinformatics, 2012 - Springer
Background We analyze phylogenetic tree building methods from molecular sequences
(PTMS). These are methods which base their construction solely on sequences, coding DNA …

The future of codon models in studies of molecular function: ancestral reconstruction, and clade models of functional divergence

BSW Chang, J Du, CJW Weadick… - Codon evolution …, 2012 - books.google.com
Likelihood-based codon models of sequence evolution have been the focus of much
excitement and development in recent years (Anisimova and Kosiol, 2009). Most attention …