Precision medicine and drug optimization in adult inflammatory bowel disease patients
S Vieujean, E Louis - Therapeutic Advances in …, 2023 - journals.sagepub.com
Inflammatory bowel diseases (IBD) encompass two main entities including ulcerative colitis
and Crohn's disease. Although having a common global pathophysiological mechanism …
and Crohn's disease. Although having a common global pathophysiological mechanism …
GABAergic signaling in alcohol use disorder and withdrawal: pathological involvement and therapeutic potential
Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the
global disease burden, contributes substantially to societal and economic costs, and leads …
global disease burden, contributes substantially to societal and economic costs, and leads …
Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention
ND Volkow, C Blanco - World Psychiatry, 2023 - Wiley Online Library
Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …
Psilocybin-induced changes in neural reactivity to alcohol and emotional cues in patients with alcohol use disorder: an fMRI pilot study
This pilot study investigated psilocybin-induced changes in neural reactivity to alcohol and
emotional cues in patients with alcohol use disorder (AUD). Participants were recruited from …
emotional cues in patients with alcohol use disorder (AUD). Participants were recruited from …
Microbiome alterations in alcohol use disorder and alcoholic liver disease
K Litwinowicz, A Gamian - International Journal of Molecular Sciences, 2023 - mdpi.com
Microbiome alterations are emerging as one of the most important factors that influence the
course of alcohol use disorder (AUD). Recent advances in bioinformatics enable more …
course of alcohol use disorder (AUD). Recent advances in bioinformatics enable more …
Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review
PV Fischler, M Soyka, E Seifritz… - Frontiers in …, 2022 - frontiersin.org
Compounds known to be successful in the treatment of alcohol use disorder include the
aversive agent, Disulfiram, the glutamatergic NMDA receptor antagonist, Acamprosate, and …
aversive agent, Disulfiram, the glutamatergic NMDA receptor antagonist, Acamprosate, and …
Neurosteroids (allopregnanolone) and alcohol use disorder: from mechanisms to potential pharmacotherapy
Abstract Alcohol Use Disorder (AUD) is a multifaceted relapsing disorder that is commonly
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …
Testing pharmacotherapies for alcohol use disorder with cue exposure paradigms: A systematic review and quantitative synthesis of human laboratory trial …
Alcohol cue exposure is a widely used experimental paradigm for screening
pharmacotherapies for alcohol use disorder (AUD). Medication‐related reductions in cue …
pharmacotherapies for alcohol use disorder (AUD). Medication‐related reductions in cue …
Drug repurposing of generic drugs: challenges and the potential role for government
Drug repurposing is the process of identifying a new use for an existing drug or active
substance in an indication outside the scope of the original indication. Drug repurposing has …
substance in an indication outside the scope of the original indication. Drug repurposing has …
A Bayesian meta-analysis of topiramate's effectiveness for individuals with alcohol use disorder
Background: Topiramate (TPM) has the potential to become one of the most prominent
treatment options for alcohol use disorder (AUD). We investigated the efficacy of TPM for …
treatment options for alcohol use disorder (AUD). We investigated the efficacy of TPM for …