Water dynamics in the hydration shells of biomolecules

D Laage, T Elsaesser, JT Hynes - Chemical Reviews, 2017 - ACS Publications
The structure and function of biomolecules are strongly influenced by their hydration shells.
Structural fluctuations and molecular excitations of hydrating water molecules cover a broad …

Water as an active constituent in cell biology

P Ball - Chemical reviews, 2008 - ACS Publications
When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

[HTML][HTML] A suite of tutorials for the WESTPA rare-events sampling software [Article v1. 0]

AT Bogetti, B Mostofian, A Dickson… - Living journal of …, 2019 - ncbi.nlm.nih.gov
The weighted ensemble (WE) strategy has been demonstrated to be highly efficient in
generating pathways and rate constants for rare events such as protein folding and protein …

Surface-enhanced Raman spectroscopy of DNA

A Barhoumi, D Zhang, F Tam… - Journal of the American …, 2008 - ACS Publications
We report a method for obtaining highly reproducible surface-enhanced Raman
spectroscopy (SERS) of single and double-stranded thiolated DNA oligomers. Following a …

Ions and RNA folding

DE Draper, D Grilley, AM Soto - Annu. Rev. Biophys. Biomol …, 2005 - annualreviews.org
▪ Abstract The problem of how ions influence the folding of RNA into specific tertiary
structures is being addressed from both thermodynamic (by how much do different salts …

Roles of non-canonical structures of nucleic acids in cancer and neurodegenerative diseases

H Tateishi-Karimata, N Sugimoto - Nucleic Acids Research, 2021 - academic.oup.com
Cancer and neurodegenerative diseases are caused by genetic and environmental factors.
Expression of tumour suppressor genes is suppressed by mutations or epigenetic silencing …

Use of ionic liquids in protein and DNA chemistry

SK Shukla, JP Mikkola - Frontiers in Chemistry, 2020 - frontiersin.org
Ionic liquids (ILs) have been receiving much attention as solvents in various areas of
biochemistry because of their various beneficial properties over the volatile solvents and ILs …

Molecular dynamics simulations of nucleic acids with a generalized Born solvation model

V Tsui, DA Case - Journal of the American Chemical Society, 2000 - ACS Publications
A generalized Born (GB) model has been applied to molecular dynamics simulations of the
A-and B-forms of a duplex DNA d (CCAACGTTGG) 2 and the corresponding duplex RNA r …

Solvation and hydration of proteins and nucleic acids: a theoretical view of simulation and experiment

V Makarov, BM Pettitt, M Feig - Accounts of chemical research, 2002 - ACS Publications
Many theoretical, computational, and experimental techniques recently have been
successfully used for description of the solvent distribution around macromolecules. In this …

Molecular dynamics simulation of nucleic acids: successes, limitations, and promise

TE Cheatham III, MA Young - Biopolymers: Original Research …, 2000 - Wiley Online Library
In the last five years we have witnessed a significant increase in the number publications
describing accurate and reliable all‐atom molecular dynamics simulations of nucleic acids …