We discuss new approaches to the early detection of keratoconus and recent investigations
regarding the nature of its pathophysiology. We review the current evidence for its complex …

Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

The UK Biobank is a prospective study of 502,543 individuals, combining extensive
phenotypic and genotypic data with streamlined access for researchers around the world …

Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …

No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Keratoconus has been classically defined as a progressive, non-inflammatory condition,
which produces a thinning and steepening of the cornea. Its pathophysiological …

Keratoconus (KC) is a common degenerative condition that frequently results in visual loss
with an onset typically in early adulthood. It is the single most common reason for …

This review article provides a comprehensive overview of the advancements in using
nanosuspensions for controlled drug delivery in ophthalmology. It highlights the significance …

Keratoconus is a progressive eye disorder primarily affecting individuals in adolescence and
early adulthood. The ectatic changes in the cornea cause thinning and cone-like steepening …

Recent studies have shown that alterations in corneal biomechanical properties are
associated with corneal pathologies, particularly corneal ectasia. Moreover, these …