The effect of SSRIs on unconditioned anxiety: a systematic review and meta-analysis of animal studies

EJ Heesbeen, T van Kampen, PM Verdouw… - …, 2024 - Springer
Rationale Selective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for
anxiety-like disorders. However, which aspects of anxiety are affected by SSRIs is not yet …

Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens

S Puig, X Xue, R Salisbury, MA Shelton, SM Kim… - Molecular …, 2023 - nature.com
Opioid craving and relapse vulnerability is associated with severe and persistent sleep and
circadian rhythm disruptions. Understanding the neurobiological underpinnings of circadian …

[HTML][HTML] A Review of Limbic System-Associated Membrane Protein in Tumorigenesis

KW Sinopole, K Babcock, A Dobi, G Petrovics - Biomedicines, 2024 - mdpi.com
Purpose of Review: This review aims to describe the role of limbic system-associated
membrane protein (LSAMP) in normal-and pathophysiology, and its potential implications in …
K Singh, M Jayaram, A Hanumantharaju, T Tõnissoo… - Scientific Reports, 2024 - nature.com
Deletions and malfunctions of the IgLON family of cell adhesion molecules are associated
with anatomical, behavioral, and metabolic manifestations of neuropsychiatric disorders. We …

Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to …

M Kaare, M Jayaram, T Jagomäe, K Singh, K Kilk… - Brain Sciences, 2022 - mdpi.com
In GWAS studies, the neural adhesion molecule encoding the neuronal growth regulator 1
(NEGR1) gene has been consistently linked with both depression and obesity. Although the …

Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior

PB Chen, R Chen, N LaPierre, Z Chen, J Mefford… - Cell Genomics, 2024 - cell.com
Knowing the genes involved in quantitative traits provides an entry point to understanding
the biological bases of behavior, but there are very few examples where the pathway from …

Alternative promoter use governs the expression of IgLON cell adhesion molecules in histogenetic fields of the embryonic mouse brain

T Jagomäe, K Singh, MA Philips, M Jayaram… - International Journal of …, 2021 - mdpi.com
The members of the IgLON superfamily of cell adhesion molecules facilitate fundamental
cellular communication during brain development, maintain functional brain circuitry, and …

Uncovering circadian rhythm disruptions of synaptic proteome signaling in prefrontal cortex and nucleus accumbens associated with opioid use disorder

S Puig, X Xue, R Salisbury, MA Shelton, SM Kim… - bioRxiv, 2023 - biorxiv.org
Opioid craving and the vulnerability to relapse is associated with severe and persistent
disruptions to sleep and circadian rhythms. Investigations into the cellular and molecular …

Integrative transcriptomics reveals layer 1 astrocytes altered in schizophrenia

J Leon, S Yoshinaga, M Hino, A Nagaoka, Y Ando… - bioRxiv, 2024 - biorxiv.org
Schizophrenia is one of the most prevalent psychiatric disorders with unclear
pathophysiology despite a century-long history of intense research. Schizophrenia affects …