Drug resistant epilepsy (DRE) is defined as the persistence of seizures despite at least two
syndrome-adapted antiseizure drugs (ASD) used at efficacious daily dose. Despite the …

Cytochrome P450 (CYP) enzymes are responsible for the metabolism of many exogenous
and endogenous compounds. CYPs are abundant in the liver and are also expressed in …

Abstract Objective To validate the Chinese version of the Generalized Anxiety Disorder-7
(GAD-7) in Chinese people with epilepsy (PWE). Methods A consecutive cohort of PWE from …

This revision of the 2005 British Association for Psychopharmacology guidelines for the
evidence-based pharmacological treatment of anxiety disorders provides an update on key …

Objective To examine the risk of emotional and behavioral problems among children with a
chronic physical illness. Methods Random-effects meta-analysis was computed to integrate …

Objective Generalized anxiety disorder (GAD) in people with epilepsy (PWE) is
underdiagnosed and undertreated. The GAD-7 is a screening questionnaire to detect GAD …

Purpose: In a nationally representative population‐based study in England, we estimated
the burden of psychiatric and neurodevelopmental comorbidities in people with epilepsy …

Background Research suggests that people with epilepsy (PWE) are more likely to
experience depression and anxiety than the general population. Given the adversity …

Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover,
the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities …

Temporal lobe epilepsy is the most common and often devastating form of human epilepsy.
The molecular mechanism underlying the development of temporal lobe epilepsy remains …