The emergence of N-heterocyclic carbenes as ligands across the Periodic Table had an
impact on various aspects of the coordination, organometallic, and catalytic chemistry of the …

Pioneered by Huisgen in the 1960s, 1 the 1, 3-dipolar cycloaddition reaction between
acetylenes and azides was brought back into focus by Sharpless and others2 when they …

Quantification and variation of characteristic properties of different ligand classes is an
exciting and rewarding research field. N‐Heterocyclic carbenes (NHCs) are of special …

Electronic and steric ligand effects both play major roles in organometallic chemistry and
consequently in metal-mediated catalysis. Quantifying such parameters is of interest to …

Water is one of the most abundant molecules on earth. It is inexpensive, especially when
compared to organic solvents, nonflammable, and nontoxic, it has a large heat capacity, and …

Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …

A new water soluble Cu (I) complex that exhibits a versatile and high catalytic activity in the
Huisgen cycloadditions of azides and terminal alkynes in aqueous media under mild …

The first examples of heteroleptic bis-N-heterocyclic carbene (NHC) copper (I) complexes
and a mixed NHC–phosphine Cu complex are reported. These complexes are easily …

The concept of click chemistry represented by the formation of the 1, 2, 3-triazole core has
found wide application in drug discovery, particularly in the early discovery phases and the …

In this study, we described the synthesis of 1, 4-and 1, 5-disubstituted-1, 2, 3-triazolo-
nucleosides from various alkynes with 1′-azido-2′, 3′, 5′-tri-O-acetylribose using either …