Glutathione-depleting nanomedicines for synergistic cancer therapy
X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
Polyoxometalates as potential next‐generation metallodrugs in the combat against cancer
Polyoxometalates (POMs) are an emerging class of inorganic metal oxides, which over the
last decades demonstrated promising biological activities by the virtue of their great diversity …
last decades demonstrated promising biological activities by the virtue of their great diversity …
Polyoxometalate-based radiosensitization platform for treating hypoxic tumors by attenuating radioresistance and enhancing radiation response
Radioresistance is one of the undesirable impediments in hypoxic tumors, which sharply
diminishes the therapeutic effectiveness of radiotherapy and eventually results in the failure …
diminishes the therapeutic effectiveness of radiotherapy and eventually results in the failure …
Polyoxometalates impact as anticancer agents
Polyoxometalates (POMs) are oxoanions of transition metal ions, such as V, Mo, W, Nb, and
Pd, forming a variety of structures with a wide range of applications. Herein, we analyzed …
Pd, forming a variety of structures with a wide range of applications. Herein, we analyzed …
Polyoxometalates in biomedicine: Update and overview
MB Čolović, M Lacković, J Lalatović… - Current medicinal …, 2020 - ingentaconnect.com
Background: Polyoxometalates (POMs) are negatively charged metal-oxo clusters of early
transition metal ions in high oxidation states (eg, WVI, MoVI, VV). POMs are of interest in the …
transition metal ions in high oxidation states (eg, WVI, MoVI, VV). POMs are of interest in the …
The future of polyoxymetalates for biological and chemical apllications
This paper reports the most interesting applications of polyoxometalates (POMs) over the
last five years, highlighting the relationship between their complex nature, properties, and …
last five years, highlighting the relationship between their complex nature, properties, and …
A survey of the different roles of polyoxometalates in their interaction with amino acids, peptides and proteins
M Arefian, M Mirzaei, H Eshtiagh-Hosseini… - Dalton …, 2017 - pubs.rsc.org
One of the most attractive areas in inorganic chemistry is the synthesis of polyoxometalates
(POMs) exhibiting new properties and applications. Since the impact of POMs in …
(POMs) exhibiting new properties and applications. Since the impact of POMs in …
The future is bright for polyoxometalates
M Aureliano - BioChem, 2022 - mdpi.com
Polyoxometalates (POMs) are clusters of units of oxoanions of transition metals, such as Mo,
W, V and Nb, that can be formed upon acidification of neutral solutions. Once formed, some …
W, V and Nb, that can be formed upon acidification of neutral solutions. Once formed, some …
Promising application of polyoxometalates in the treatment of cancer, infectious diseases and Alzheimer's disease
X Wang, S Wei, C Zhao, X Li, J **, X Shi, Z Su… - JBIC Journal of …, 2022 - Springer
As shown in studies conducted in recent decades, polyoxometalates (POMs), as inorganic
metal oxides, have promising biological activities, including antitumor, anti-infectious and …
metal oxides, have promising biological activities, including antitumor, anti-infectious and …
Polyoxometalate nanoclusters: a potential preventative and therapeutic drug for inflammatory bowel disease
Although the etiology and pathogenesis of refractory inflammatory bowel diseases (IBD) are
still largely suspended, elimination of reactive oxygen species (ROS) in inflamed colon has …
still largely suspended, elimination of reactive oxygen species (ROS) in inflamed colon has …