Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Advanced nitric oxide generating nanomedicine for therapeutic applications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …
Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
Light: a magical tool for controlled drug delivery
Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …
nature, ease of application, and exquisite temporal and spatial control. Great progress is …
Photoacoustic cavitation‐ignited reactive oxygen species to amplify peroxynitrite burst by photosensitization‐free polymeric nanocapsules
Z Wang, M Zhan, W Li, C Chu, D **ng… - Angewandte Chemie …, 2021 - Wiley Online Library
Photoacoustic (PA) technology can transform light energy into acoustic wave, which can be
used for either imaging or therapy that depends on the power density of pulsed laser. Here …
used for either imaging or therapy that depends on the power density of pulsed laser. Here …
Orchestrating nitric oxide and carbon monoxide signaling molecules for synergistic treatment of MRSA infections
L Gao, J Cheng, Z Shen, G Zhang… - Angewandte Chemie …, 2022 - Wiley Online Library
The local delivery of gaseous signaling molecules (GSMs) has shown promising therapeutic
potential. However, although GSMs have a subtle interplay in physiological and pathological …
potential. However, although GSMs have a subtle interplay in physiological and pathological …
Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing
Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs),
often stay in a state of pathological inflammation and suffer from persistent infection, excess …
often stay in a state of pathological inflammation and suffer from persistent infection, excess …
Red‐light‐mediated photoredox catalysis enables self‐reporting nitric oxide release for efficient antibacterial treatment
Nitric oxide (NO) serves as a key regulator of many physiological processes and as a potent
therapeutic agent. The local delivery of NO is important to achieve target therapeutic …
therapeutic agent. The local delivery of NO is important to achieve target therapeutic …
Killing three birds with one stone: Near-infrared light triggered nitric oxide release for enhanced photodynamic and anti-inflammatory therapy in refractory keratitis
H Zhang, W Jiang, Y Peng, J Yang, X Chu, Z Long, R Li… - Biomaterials, 2022 - Elsevier
Stubborn resistant bacteria, bacterial biofilms and severe inflammation are challenging
issues in refractory keratitis treatment. Herein, we design a multifunctional near-infrared light …
issues in refractory keratitis treatment. Herein, we design a multifunctional near-infrared light …