Advances in colon-targeted nano-drug delivery systems: challenges and solutions

M Naeem, UA Awan, F Subhan, J Cao… - Archives of pharmacal …, 2020 - Springer
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …

[HTML][HTML] Insight to drug delivery aspects for colorectal cancer

A Gulbake, A Jain, A Jain, A Jain… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide in human
beings. Surgery, chemotherapy, radiotherapy and targeted therapies are the conventional …

Dual-drug delivery system based on the hydrogels of alginate and sodium carboxymethyl cellulose for colorectal cancer treatment

Y Sheng, J Gao, ZZ Yin, J Kang, Y Kong - Carbohydrate Polymers, 2021 - Elsevier
To improve the efficacy of chemotherapy and relieve the pain associated with colorectal
cancer, a dual-drug delivery system (DDDS) is proposed. In this system, methotrexate (MTX) …

Deformable liposomal hydrogel for dermal and transdermal delivery of meloxicam

ZJ Zhang, T Osmałek… - International Journal of …, 2020 - Taylor & Francis
Background and Aim Meloxicam (MX) is a potent hydrophobic non-steroidal anti-
inflammatory drug used to reduce inflammation and pain. However, its oral dosage form can …

Cationic liposomes mediated transdermal delivery of meloxicam and ketoprofen: Optimization of the composition, in vitro and in vivo assessment of efficiency

DA Kuznetsova, LA Vasileva, GA Gaynanova… - International Journal of …, 2021 - Elsevier
New liposomes modified with pyrrolidinium surfactants containing a hydroxyethyl fragment
(C n PB, n= 12, 14, 16) were prepared for transdermal delivery of non-steroidal anti …

Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system

R Mehta, A Chawla, P Sharma… - Journal of advanced …, 2013 - journals.lww.com
The purpose of the present investigation was to prepare matrix tablets of naproxen using a
hydrophobic polymer, ie, Eudragit RLPO, RSPO, and combination of both, by wet …

Microfluidic manipulation of core/shell nanoparticles for oral delivery of chemotherapeutics: a new treatment approach for colorectal cancer

MM Hasani-Sadrabadi, S Taranejoo… - Advanced …, 2016 - epublications.marquette.edu
A microfluidics approach to synthesize core–shell nanocarriers with high pH tunability is
described. The sacrificial shell protects the core layer with the drugs and prevents their …

Topical delivery of meloxicam using liposome and microemulsion formulation approaches

J Zhang, A Froelich, B Michniak-Kohn - Pharmaceutics, 2020 - mdpi.com
The aim of this study is to develop, characterize and compare conventional liposome,
deformable liposome (transfersome) and microemulsion formulations as potential topical …

Recent trends in assessment of cellulose derivatives in designing novel and nanoparticulate-based drug delivery systems for improvement of oral health

KM Hosny, HM Alkhalidi, WS Alharbi, S Md, AM Sindi… - Polymers, 2021 - mdpi.com
Natural polymers are revolutionizing current pharmaceutical dosage forms design as
excipient and gained huge importance because of significant influence in formulation …

Triumph against cancer: invading colorectal cancer with nanotechnology

P Vinchhi, MM Patel - Expert Opinion on Drug Delivery, 2021 - Taylor & Francis
Introduction Recent statistics have reported colorectal cancer (CRC) as the second leading
cause of cancer-associated deaths in the world. Early diagnosis of CRC may help to reduce …