Mechanisms of airway remodeling

N Hirota, JG Martin - Chest, 2013 - Elsevier
Airway remodeling comprises the structural changes of airway walls, induced by repeated
injury and repair processes. It is characterized by the changes of tissue, cellular, and …

Equine asthma: current understanding and future directions

L Couetil, JM Cardwell, R Leguillette… - Frontiers in veterinary …, 2020 - frontiersin.org
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the
latest information on Equine Asthma and provide future research directions. Current clinical …

Inflammatory airway disease of horses—revised consensus statement

LL Couëtil, JM Cardwell, V Gerber… - Journal of veterinary …, 2016 - Wiley Online Library
The purpose of this manuscript is to revise and update the previous consensus statement on
inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific …

Equine asthma: Integrative biologic relevance of a recently proposed nomenclature

S Bond, R Léguillette, EA Richard… - Journal of veterinary …, 2018 - Wiley Online Library
The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …

Tracheobronchomalacia and excessive dynamic airway collapse: current concepts and future directions

A Aslam, J De Luis Cardenas, RJ Morrison… - Radiographics, 2022 - pubs.rsna.org
Tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC) are airway
abnormalities that share a common feature of expiratory narrowing but are distinct …

Asthma “of horses and men”—How can equine heaves help us better understand human asthma immunopathology and its functional consequences?

M Bullone, JP Lavoie - Molecular immunology, 2015 - Elsevier
Animal models have been studied to unravel etiological, immunopathological, and genetic
attributes leading to asthma. However, while experiments in which the disease is artificially …

The equine asthma model of airway remodeling: from a veterinary to a human perspective

M Bullone, JP Lavoie - Cell and tissue research, 2020 - Springer
Human asthma is a complex and heterogeneous disorder characterized by chronic
inflammation, bronchospasm and airway remodeling. The latter is a major determinant of the …

An official American Thoracic Society research statement: current challenges facing research and therapeutic advances in airway remodeling

YS Prakash, AJ Halayko, R Gosens… - American Journal of …, 2017 - atsjournals.org
Background: Airway remodeling (AR) is a prominent feature of asthma and other obstructive
lung diseases that is minimally affected by current treatments. The goals of this Official …

Inflammation‐dependent and independent airway remodelling in asthma

JG Elliot, PB Noble, T Mauad, TR Bai… - …, 2018 - Wiley Online Library
Background and objective The pathology of asthma is characterized by airway inflammation
(granulocytic (GA) or paucigranulocytic (PGA)) and remodelling of airway structures …

Effect of different doses of inhaled ciclesonide on lung function, clinical signs related to airflow limitation and serum cortisol levels in horses with experimentally …

JP Lavoie, M Bullone, N Rodrigues… - Equine Veterinary …, 2019 - Wiley Online Library
Background Inhaled corticosteroids are effective for the treatment of equine asthma but they
induce cortisol suppression with potential side effects. Objectives To study the efficacy of …