The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q **ong, Z **… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells
D Xu, Y Ma, X Han, Y Chen - Journal of hazardous materials, 2021 - Elsevier
There is a growing concern regarding the toxic effects of nanoplastics (NPs) on aquatic and
marine organism, while relatively few studies about their toxicity evaluation on mammals are …
marine organism, while relatively few studies about their toxicity evaluation on mammals are …
[HTML][HTML] The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function
L Ma, T Chen, X Zhang, Y Miao, X Tian, K Yu, X Xu… - Redox Biology, 2021 - Elsevier
The biological functions of N6-methyladenosine (m 6 A) RNA methylation are mainly
dependent on the reader; however, its role in lung tumorigenesis remains unclear. Here, we …
dependent on the reader; however, its role in lung tumorigenesis remains unclear. Here, we …
Circular RNA cIARS regulates ferroptosis in HCC cells through interacting with RNA binding protein ALKBH5
Z Liu, Q Wang, X Wang, Z Xu, X Wei, J Li - Cell death discovery, 2020 - nature.com
Circular RNAs (circRNAs) are a novel and unique class of noncoding RNAs that are back-
spliced from pre-mRNAs. It has been confirmed that circRNAs are involved in various …
spliced from pre-mRNAs. It has been confirmed that circRNAs are involved in various …
The RNA m6A writer WTAP in diseases: structure, roles, and mechanisms
Q Huang, J Mo, Z Liao, X Chen, B Zhang - Cell Death & Disease, 2022 - nature.com
Abstract N6-methyladenosine (m6A) is a widely investigated RNA modification in studies on
the “epigenetic regulation” of mRNAs that is ubiquitously present in eukaryotes. Abnormal …
the “epigenetic regulation” of mRNAs that is ubiquitously present in eukaryotes. Abnormal …
Surmounting cancer drug resistance: New insights from the perspective of N6-methyladenosine RNA modification
Despite the development of targeted therapy, drug resistance remains a primary hindrance
to curative treatment of various cancers. Among several novel approaches to overcome drug …
to curative treatment of various cancers. Among several novel approaches to overcome drug …
The mechanism of m6A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene
S Liu, Q Li, G Li, Q Zhang, L Zhuo, X Han… - Cell death & …, 2020 - nature.com
Abstract N6-methyladenosine (m6A) modification can alter gene expression by regulating
RNA splicing, stability, translocation, and translation. Emerging evidence shows that m6A …
RNA splicing, stability, translocation, and translation. Emerging evidence shows that m6A …
Roles of RNA methylation on tumor immunity and clinical implications
M Zhang, J Song, W Yuan, W Zhang, Z Sun - Frontiers in immunology, 2021 - frontiersin.org
RNA methylation is a kind of RNA modification that exists widely in eukaryotes and
prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA. According to the …
prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA. According to the …
[HTML][HTML] Role of m6A modification in female infertility and reproductive system diseases
J Chen, Y Fang, Y Xu, H Sun - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Gamete abnormalities and reproductive system tumors have become a dominant cause of
infertility, troubling people globally. In recent years, increasing evidence emerged and found …
infertility, troubling people globally. In recent years, increasing evidence emerged and found …