Eukaryotic cell size control and its relation to biosynthesis and senescence

S **e, M Swaffer, JM Skotheim - Annual review of cell and …, 2022 - annualreviews.org
The most fundamental feature of cellular form is size, which sets the scale of all cell
biological processes. Growth, form, and function are all necessarily linked in cell biology, but …

Fundamental principles in bacterial physiology—history, recent progress, and the future with focus on cell size control: a review

S Jun, F Si, R Pugatch, M Scott - Reports on Progress in Physics, 2018 - iopscience.iop.org
Bacterial physiology is a branch of biology that aims to understand overarching principles of
cellular reproduction. Many important issues in bacterial physiology are inherently …

[HTML][HTML] Mechanistic origin of cell-size control and homeostasis in bacteria

F Si, G Le Treut, JT Sauls, S Vadia, PA Levin, S Jun - Current Biology, 2019 - cell.com
Evolutionarily divergent bacteria share a common phenomenological strategy for cell-size
homeostasis under steady-state conditions. In the presence of inherent physiological …

Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation

DN Macklin, TA Ahn-Horst, H Choi, NA Ruggero… - Science, 2020 - science.org
INTRODUCTION The generation of biological data is presenting us with one of the most
demanding analysis challenges the world has ever faced, not only in terms of storage and …

Size control in mammalian cells involves modulation of both growth rate and cell cycle duration

C Cadart, S Monnier, J Grilli, PJ Sáez… - Nature …, 2018 - nature.com
Despite decades of research, how mammalian cell size is controlled remains unclear
because of the difficulty of directly measuring growth at the single-cell level. Here we report …

Cell size and growth regulation in the Arabidopsis thaliana apical stem cell niche

L Willis, Y Refahi, R Wightman, B Landrein… - Proceedings of the …, 2016 - pnas.org
Cell size and growth kinetics are fundamental cellular properties with important
physiological implications. Classical studies on yeast, and recently on bacteria, have …

Sizing up the bacterial cell cycle

L Willis, KC Huang - Nature Reviews Microbiology, 2017 - nature.com
It is remarkable how robustly a bacterial species can maintain its preferred size. This
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …

The bacterial cell cycle, chromosome inheritance and cell growth

R Reyes-Lamothe, DJ Sherratt - Nature Reviews Microbiology, 2019 - nature.com
All viable bacterial cells, whether they divide symmetrically or asymmetrically, must
coordinate their growth, division, cell volume and shape with the inheritance of the genome …

[HTML][HTML] Cell size homeostasis: Metabolic control of growth and cell division

M Björklund - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
Joint regulation of growth rate and cell division rate determines cell size. Here we discuss
how animal cells achieve cell size homeostasis potentially involving multiple signaling …

Nutrient availability as an arbiter of cell size

DR Kellogg, PA Levin - Trends in cell biology, 2022 - cell.com
Pioneering work carried out over 60 years ago discovered that bacterial cell size is
proportional to the growth rate set by nutrient availability. This relationship is traditionally …