Pigmentation diseases can lead to significant color differences between the affected part
and the normal part, resulting in severe psychological and emotional distress among …

Red hair has been linked to altered sensitivity to pain, analgesics, and hypnotics. This
alteration may be impacted by variants in the melanocortin-1 receptor (MC1R) gene, which …

Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …

Sex differences for chronic back pain (cBP) have been reported, with females usually
exhibiting greater morbidity, severity, and poorer response to treatment. Genetic factors …

The adenosine triphosphate (ATP)-gated channel P2X7 is encoded by a gene enriched for
common nonsynonymous variants. Many of these variants have functional cellular effects …

The MC1R protein is a receptor found in melanocytes that plays a role in melanin synthesis.
Mutations in this protein can impact hair color, skin tone, tanning ability, and increase the …

The melanocortin receptors are G-protein-coupled receptors, which are essential
components of the hypothalamic–pituitary–adrenal axis, and they mediate the actions of …

Melanocortin 1 receptor (MC1R) is thought to be a marker of poor prognosis and a potential
target for the treatment of melanoma. Studies have found that MC1R promotes several tumor …

Genetic variation in melanocortin-1 receptor (MC1R) has a known role in red hair. Studies
on responses to noxious stimuli in red-haired individuals have also been conducted, with …

Reptiles showcase an extensive array of skin colours and patterns, yet little is known about
the genetics of reptile colouration. Here, we investigate the genetic basis of the Clown colour …