Brain connectomics: time for a molecular imaging perspective?

A Sala, A Lizarraga, SP Caminiti, VD Calhoun… - Trends in cognitive …, 2023 - cell.com
In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …

The metabolic costs of cognition

SD Jamadar, A Behler, H Deery… - Trends in Cognitive …, 2024 - cell.com
Cognition and behavior are emergent properties of brain systems that seek to maximize
complex and adaptive behaviors while minimizing energy utilization. Different species …

High-temporal resolution functional PET/MRI reveals coupling between human metabolic and hemodynamic brain response

A Hahn, MB Reed, C Vraka, GM Godbersen… - European Journal of …, 2024 - Springer
Purpose Positron emission tomography (PET) provides precise molecular information on
physiological processes, but its low temporal resolution is a major obstacle. Consequently …

Image reconstruction using UNET-transformer network for fast and low-dose PET scans

S Kaviani, A Sanaat, M Mokri, C Cohalan… - … Medical Imaging and …, 2023 - Elsevier
Introduction Low-dose and fast PET imaging (low-count PET) play a significant role in
enhancing patient safety, healthcare efficiency, and patient comfort during medical imaging …

Reconfiguration of metabolic connectivity in ageing

HA Deery, EX Liang, MN Siddiqui, G Murray… - Communications …, 2024 - nature.com
Abstract Information transfer across the brain has a high energetic cost and requires efficient
glucose metabolism. Here we use recently developed high temporal resolution functional …

Spatiotemporal topological correspondence between blood oxygenation and glucose metabolism revealed by simultaneous fPET-fMRI in brain's white matter

J Li, GR Wu, M Shi, J **a, Y Meng, S Yang… - Cerebral …, 2023 - academic.oup.com
White matter (WM) makes up half of the human brain. Compelling functional MRI evidence
indicates that white matter exhibits neural activation and synchronization via a …

Non-invasive assessment of stimulation-specific changes in cerebral glucose metabolism with functional PET

GM Godbersen, P Falb, S Klug, LR Silberbauer… - European Journal of …, 2024 - Springer
Purpose Functional positron emission tomography (fPET) with [18F] FDG allows
quantification of stimulation-induced changes in glucose metabolism independent of …

Identification of resting-state networks using dynamic brain perfusion SPECT imaging: A fSPECT case report

M Doyen, G Hossu, S Heyer, T Zaragori… - Frontiers in Human …, 2023 - frontiersin.org
Connectivity studies with nuclear medicine systems are scarce in literature. They mainly
employ PET imaging and group level analyses due to the low temporal resolution of PET …

Metabolic connectivity in ageing

HA Deery, E Liang, MN Siddiqui, G Murray, K Voigt… - bioRxiv, 2024 - biorxiv.org
Abstract Information transfer across the brain has a high energetic cost and requires the
efficient use of glucose. Positron emission tomography (PET) studies have shown that …

A Unified Approach for Identifying PET-based Neuronal Activation and Molecular Connectivity with the functional PET toolbox

A Hahn, MB Reed, C Milz, P Falb, M Murgas… - BioRxiv, 2024 - biorxiv.org
Purpose: Functional PET (fPET) enables the identification of stimulation-specific changes of
various physiological processes (eg, glucose metabolism, neurotransmitter synthesis) as …