Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

The efficacy of psychotherapies and pharmacotherapies for mental disorders in adults: an umbrella review and meta‐analytic evaluation of recent meta‐analyses

F Leichsenring, C Steinert, S Rabung… - World …, 2022 - Wiley Online Library
Mental disorders represent a worldwide public health concern. Psychotherapies and
pharmacotherapies are recommended as first line treatments. However, evidence has …

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

GS Malhi, E Bell, D Bassett, P Boyce… - Australian & New …, 2021 - journals.sagepub.com
Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Effects of psilocybin-assisted therapy on major depressive disorder: a randomized clinical trial

AK Davis, FS Barrett, DG May, MP Cosimano… - JAMA …, 2021 - jamanetwork.com
Importance Major depressive disorder (MDD) is a substantial public health burden, but
current treatments have limited effectiveness and adherence. Recent evidence suggests that …

Selective serotonin reuptake inhibitors and adverse effects: a narrative review

AN Edinoff, HA Akuly, TA Hanna, CO Ochoa… - Neurology …, 2021 - mdpi.com
Depression is the most prevalent psychiatric disorder in the world, affecting 4.4% of the
global population. Despite an array of treatment modalities, depressive disorders remain …

[HTML][HTML] More treatment but no less depression: The treatment-prevalence paradox

J Ormel, SD Hollon, RC Kessler, P Cuijpers… - Clinical psychology …, 2022 - Elsevier
Treatments for depression have improved, and their availability has markedly increased
since the 1980s. Mysteriously the general population prevalence of depression has not …

A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression

P Cuijpers, H Noma, E Karyotaki, CH Vinkers… - World …, 2020 - Wiley Online Library
No network meta‐analysis has examined the relative effects of psychotherapies,
pharmacotherapies and their combination in the treatment of adult depression, while this is a …

Increased risk for COVID‐19 breakthrough infection in fully vaccinated patients with substance use disorders in the United States between December 2020 and …

L Wang, QQ Wang, PB Davis, ND Volkow… - World …, 2022 - Wiley Online Library
Individuals with substance use disorders (SUDs) are at increased risk for COVID‐19
infection and for adverse outcomes of the infection. Though vaccines are highly effective …

Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety

AK Davis, FS Barrett, RR Griffiths - Journal of contextual behavioral science, 2020 - Elsevier
Prior research has shown that acute subjective psychedelic effects are associated with both
spontaneous and intended changes in depression and anxiety. Psychedelics are also …

The efficacy and effectiveness of psychological therapies

M Barkham, MJ Lambert - Bergin and Garfield's handbook of …, 2021 - books.google.com
This chapter sets out the current status of the evidence-base for the efficacy and
effectiveness of psychological therapies. First, methods for eliciting and synthesizing …