In recent decades, mass spectrometry has moved more than ever before into the front line of
protein-centered research. After being established at the qualitative level, the more …

Recent advances in mass spectrometry (MS)-based proteomics have enabled tremendous
progress in the understanding of cellular mechanisms, disease progression, and the …

According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …

Selected reaction monitoring (SRM) is a targeted mass spectrometry technique that is
emerging in the field of proteomics as a complement to untargeted shotgun methods. SRM is …

Systems biology relies on data sets in which the same group of proteins is consistently
identified and precisely quantified across multiple samples, a requirement that is only …

The quantification of differences between two or more physiological states of a biological
system is among the most important but also most challenging technical tasks in proteomics …

Mass-spectrometry based proteomics has evolved as a promising technology over the last
decade and is undergoing a dramatic development in a number of different areas, such as; …

Over the past decade, a series of experimental strategies for mass spectrometry based
quantitative proteomics and corresponding computational methodology for the processing of …

Label‐free quantification of high mass resolution LC‐MS data has emerged as a promising
technology for proteome analysis. Computational methods are required for the accurate …