A dynamic, supramolecular view on the multivalent interaction between influenza virus and host cell
Understanding how influenza viruses traverse the mucus and recognize host cells is critical
for evaluating their zoonotic potential, and for prevention and treatment of the disease. The …
for evaluating their zoonotic potential, and for prevention and treatment of the disease. The …
A non-cytotoxic dendrimer with innate and potent anticancer and anti-metastatic activities
The structural perfection and multivalency of dendrimers have made them useful for
biodelivery and bioactivity via peripheral functionalization and the modulation of core …
biodelivery and bioactivity via peripheral functionalization and the modulation of core …
Multiscale modeling of protein membrane interactions for nanoparticle targeting in drug delivery
Highlights•Computational methods for modeling hydrodynamic factors in nanoparticle
membrane interactions in targeted drug delivery.•Computational frameworks for predicting …
membrane interactions in targeted drug delivery.•Computational frameworks for predicting …
Design principles for super selectivity using multivalent interactions
Multivalent particles have the ability to form multiple bonds to a substrate. Hence, a
multivalent interaction can be strong, even if the individual bonds are weak. This chapter …
multivalent interaction can be strong, even if the individual bonds are weak. This chapter …
Amplification free detection of SARS-CoV-2 using multi-valent binding
We present the development of electrochemical impedance spectroscopy (EIS)-based
biosensors for sensitive detection of SARS-CoV-2 RNA using multi-valent binding. By …
biosensors for sensitive detection of SARS-CoV-2 RNA using multi-valent binding. By …
Molecular Dynamics Simulation of the Nascent Polyethylene Crystallization in Confined Space: Nucleation and Lamella Orientation
S Chen, W Chen, Y Ren, J Sun, J Wang… - Macromolecules, 2022 - ACS Publications
Different nascent structures during polyethylene growth can impact the final polymer
properties. So far, the evolution of the aggregation structure of nascent polyethylene is still …
properties. So far, the evolution of the aggregation structure of nascent polyethylene is still …
Molecular dynamics study on the interfacial properties of mixtures of monomers of polyvinylpyrrolidone (PVP)-based battery binders on graphene and graphite …
This study investigates the behavior of two different mixtures of monomers of
polyvinylpyrrolidone (PVP)-based battery binders, polyvinylpyrrolidone: polyvinylidene …
polyvinylpyrrolidone (PVP)-based battery binders, polyvinylpyrrolidone: polyvinylidene …
Density control over MBD2 receptor-coated surfaces provides superselective binding of hypermethylated DNA
Using the biomarker hypermethylated DNA (hmDNA) for cancer detection requires a
pretreatment to isolate or concentrate hmDNA from nonmethylated DNA. Affinity …
pretreatment to isolate or concentrate hmDNA from nonmethylated DNA. Affinity …
Designing Multivalent Copolymers for Selective Targeting of Multicomponent Surfaces
Selective targeting of membranes with a specific receptor profile is an ongoing challenge in
targeted drug delivery. We investigate the adsorption of copolymers on a multicomponent …
targeted drug delivery. We investigate the adsorption of copolymers on a multicomponent …
Computational design of probes to detect bacterial genomes by multivalent binding
Rapid methods for diagnosis of bacterial infections are urgently needed to reduce
inappropriate use of antibiotics, which contributes to antimicrobial resistance. In many rapid …
inappropriate use of antibiotics, which contributes to antimicrobial resistance. In many rapid …