Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Cancer active targeting by nanoparticles: a comprehensive review of literature

R Bazak, M Houri, S El Achy, S Kamel… - Journal of cancer research …, 2015 - Springer
Purpose Cancer is one of the leading causes of death, and thus, the scientific community
has but great efforts to improve cancer management. Among the major challenges in cancer …

[HTML][HTML] Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

J Ghitman, EI Biru, R Stan, H Iovu - Materials & Design, 2020 - Elsevier
The concept of PLGA-lipid hybrid nanoparticles arose as a motivation for develo** drug
delivery systems with versatile physical and chemical properties, unequivocal therapeutic …

Effect of gold nanoparticle aggregation on cell uptake and toxicity

A Albanese, WCW Chan - ACS nano, 2011 - ACS Publications
Aggregation appears to be a ubiquitous phenomenon among all nanoparticles and its
influence in mediating cellular uptake and interactions remain unclear. Here we developed …

Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: a review

K Hadinoto, A Sundaresan, WS Cheow - European journal of …, 2013 - Elsevier
Lipid–polymer hybrid nanoparticles (LPNs) are core–shell nanoparticle structures
comprising polymer cores and lipid/lipid–PEG shells, which exhibit complementary …

The transferrin receptor and the targeted delivery of therapeutic agents against cancer

TR Daniels, E Bernabeu, JA Rodríguez, S Patel… - … et Biophysica Acta (BBA …, 2012 - Elsevier
BACKGROUND: Traditional cancer therapy can be successful in destroying tumors, but can
also cause dangerous side effects. Therefore, many targeted therapies are in development …

Vitamin E TPGS as a molecular biomaterial for drug delivery

Z Zhang, S Tan, SS Feng - Biomaterials, 2012 - Elsevier
d-α-tocopheryl polyethylene glycol succinate (Vitamin E TPGS, or simply TPGS) is a water-
soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E …

Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

A Mukherjee, AK Waters, P Kalyan… - International journal …, 2019 - Taylor & Francis
Lipid–polymer hybrid nanoparticles (LPHNPs) are next-generation core–shell
nanostructures, conceptually derived from both liposome and polymeric nanoparticles …

Functionalizing PLGA and PLGA derivatives for drug delivery and tissue regeneration applications

C Martins, F Sousa, F Araujo… - Advanced healthcare …, 2018 - Wiley Online Library
Abstract Poly (lactic‐co‐glycolic) acid (PLGA) is one of the most versatile biomedical
polymers, already approved by regulatory authorities to be used in human research and …