This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

The delivery of a drug to a specific organ or tissue at an efficacious concentration is the
pharmacokinetic (PK) hallmark of promoting effective pharmacological action at a target site …

Prodrugs are bioreversible, inactive drug derivatives, which have the ability to convert into a
parent drug in the body. In the past, prodrugs were used as a last option; however …

High solubility in water and physiological fluids is an indispensable requirement for the
pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well …

Abstract Background This “Anti-Obesity Medications and Investigational Agents: An Obesity
Medicine Association Clinical Practice Statement 2022” is intended to provide clinicians an …

Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms
including those in the microbial world. They are utilised as nutrients and control many …

Heartburn and acid regurgitation are the typical symptoms of gastroesophageal reflux.
Despite the availability of several treatment options, antacids remain the mainstay treatment …

OBJECTIVES: To provide guidance on the reporting of norepinephrine formulation labeling,
reporting in publications, and use in clinical practice. DESIGN: Review and task force …

Environmental impacts of the industrial revolution necessitate adoption of sustainable
practices in all areas of development. The pharmaceutical industry faces increasing …

Ribociclib (RBC) is an anticancer drug of poor aqueous solubility and low permeability. In
this study, we report the improvement in the physicochemical properties of RBC, such as …