Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Systematic evolution of ligands by exponential enrichment (SELEX) has been used to
discover thousands of aptamers since its development in 1990. Aptamers are short single …

Fast, inexpensive, and multiplexed detection of multiple nucleic acids is of great importance
to human health, yet it still represents a significant challenge. Herein, we propose a nucleic …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Aptamers are being applied as affinity reagents in analytical applications owing to their high
stability, compact size and amenability to chemical modification. Generating aptamers with …

We report a simple and rapid saliva‐based SARS‐CoV‐2 antigen test that utilizes a newly
developed dimeric DNA aptamer, denoted as DSA1N5, that specifically recognizes the spike …

Nucleic acid aptamers are oligonucleotide chains with molecular recognition properties.
Compared with antibodies, aptamers show advantages given that they are readily produced …

Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for
clinical control and treatment of virus infection. Aptamers are small single-stranded …

Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Aptamers are molecular recognition elements made of nucleic acids. Diverse synthetic
aptamers have been discovered in a large number of SELEX experiments since 1990. This …