Skeletal muscle (SM) tissue has been repetitively shown to play a major role in whole-body
glucose homeostasis and overall metabolic health. Hence, SM hypertrophy through …

Accumulation of lipid in skeletal muscle is thought to be related to the development of insulin
resistance and type 2 diabetes. Initial work in this area focused on accumulation of …

Objective Intramyocellular lipid (IMCL) storage negatively associates with insulin resistance,
albeit not in endurance-trained athletes. We investigated the putative contribution of lipid …

Excessive storage of lipid droplets (LDs) in skeletal muscles is a hallmark of type 2 diabetes.
However, LD morphology displays a high degree of subcellular heterogeneity and varies …

Rock-climbing performance is largely dependent on the endurance of the forearm flexors.
Recently, it was reported that forearm flexor endurance in elite climbers is independent of …

While short-term high intensity functional training (HIFT) effects have been established,
fitness improvements from program participation exceeding 16 weeks are unknown. This …

The discovery of perilipin (PLIN) 1 provided a major conceptual shift in the understanding of
adipose tissue lipolysis and generated intense interest in lipid droplet biology research. The …

Intramuscular lipid (IMCL) utilization during exercise was controversial as numerous studies
did not observe a decline in IMCL content post-exercise when assessed in muscle biopsies …

Conventionally viewed as energy storage depots, lipid droplets (LDs) play a central role in
muscle lipid metabolism and intracellular signaling, as recognized by recent advances in …

Triglycerides are stored within lipid droplets in skeletal muscle and can be hydrolyzed to
produce fatty acids for energy production through β-oxidation and oxidative phosphorylation …