The microbiome shapes many host traits, yet the biology of microbiomes challenges
traditional evolutionary models. Here, we illustrate how integrating the microbiome into …

Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

Abstract The NIH Human Microbiome Project (HMP) has been carried out over ten years and
two phases to provide resources, methods, and discoveries that link interactions between …

Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …

One major limitation of microbial community marker gene sequencing is that it does not
provide direct information on the functional composition of sampled communities. Here, we …

Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

Abstract Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta
cells and incorporates genetic and environmental factors, including complex genetic …

The gut microbiota benefits humans via short-chain fatty acid (SCFA) production from
carbohydrate fermentation, and deficiency in SCFA production is associated with type 2 …

The gut microbiome can influence the development of tumours and the efficacy of cancer
therapeutics,,,–; however, the multi-omics characteristics of antitumour bacterial strains have …

Many US immigrant populations develop metabolic diseases post immigration, but the
causes are not well understood. Although the microbiome plays a role in metabolic disease …