Carbon dots (CDs) are luminescent nanomaterials with unique properties that show great
potential in many applications. Herein, hollow CDs (HCDs) are prepared from bovine serum …

Tumors and associated stroma manifest mechanical properties that promote cancer.
Mechanosensation of tissue stiffness activates the Rho/ROCK pathway to increase …

Cancer targeted therapy, either alone or in combination with conventional chemotherapy,
could allow the survival of patients with neoplasms currently considered incurable. In recent …

Background Transwell-based models of the blood–brain barrier (BBB) incorporating
monolayers of human brain microvascular endothelial cells (dhBMECs) derived from …

Spinal muscular atrophy (SMA) is an inherited disease resulting in the highest mortality of
children under the age of two. SMA is caused by mutations or deletions in the survival motor …

Background and Purpose Tumour cell migration and adhesion constitute essential features
of metastasis. G‐protein coupled receptor 55 (GPR55), a lysophospholipid receptor, has …

Hair follicle morphogenesis is triggered by reciprocal interactions between hair follicle germ
(HFG) epithelial and mesenchymal layers. Here, we developed a method for large-scale …

Introduction: The Rho kinase/ROCK is critical in vital signal transduction pathways central to
many essential cellular activities. Since ROCK possess multiple substrates, modulation of …

Vascular endothelial growth factor (VEGF) plays a crucial role in tumor angiogenesis. VEGF
induces new vessel formation and tumor growth by inducing mitogenesis and chemotaxis of …

Mitochondria are the main sites of cell metabolism. Even minor pH changes may lead to
mitochondrial dysfunction and promote cell apoptosis. Mitochondrion-targeting …