Saccharomyces cerevisiae and grape juice are 'natural companions' and make a happy
wine marriage. However, this relationship can be enriched by allowing 'wild'non …

Many types of mammalian cells can aggregate and differentiate into 3‐D multicellular
spheroids when cultured in suspension or a nonadhesive environment. Compared to …

Zygomycete fungi were classified as a single phylum, Zygomycota, based on sexual
reproduction by zygospores, frequent asexual reproduction by sporangia, absence of …

Large structural variations (SVs) within genomes are more challenging to identify than
smaller genetic variants but may substantially contribute to phenotypic diversity and …

Eukaryotic genomes are generally organized in multiple chromosomes. Here we have
created a functional single-chromosome yeast from a Saccharomyces cerevisiae haploid …

Data on absolute molecule numbers will empower the modeling, understanding, and
comparison of cellular functions and biological systems. We quantified transcriptomes and …

Background The availability of multiple, essentially complete genome sequences of
prokaryotes and eukaryotes spurred both the demand and the opportunity for the …

The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of
malaria, and kills more than one million African children annually. Here we report an …

A principal challenge currently facing biologists is how to connect the complete DNA
sequence of an organism to its development and behaviour. Large-scale targeted-deletions …

Yeasts have been used for thousands of years to make fermented foods and beverages,
such as beer, wine, sake, and bread. However, the choice for a particular yeast strain or …