Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Rationale: An exaggerated or persistent inflammatory activation after myocardial infarction
(MI) leads to maladaptive healing and subsequent remodeling of the left ventricle. Foxp3+ …

A current paradigm states that monocytes circulate freely and patrol blood vessels but
differentiate irreversibly into dendritic cells (DCs) or macrophages upon tissue entry. Here …

Factor XIII (FXIII) is unique among clotting factors for a number of reasons: 1) it is a
protransglutaminase, which becomes activated in the last stage of coagulation; 2) it works …

Inflammatory cell recruitment after myocardial infarction needs to be tightly controlled to
permit infarct healing while avoiding fatal complications such as cardiac rupture. Growth …

Background—Exaggerated and prolonged inflammation after myocardial infarction (MI)
accelerates left ventricular remodeling. Inflammatory pathways may present a therapeutic …

Acute myocardial infarction (AMI) is a common and lethal heart disease, and the recruitment
of fibroblastic cells to the infarct region is essential for the cardiac healing process. Although …

Objectives: The aim of this study was to test whether blood monocytosis in mice with
atherosclerosis affects infarct healing. Background: Monocytes are cellular protagonists of …

The human transglutaminase (TG) family consists of a structural protein, protein 4.2, that
lacks catalytic activity, and eight zymogens/enzymes, designated factor XIII-A (FXIII-A) and …