Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Ascorbic acid: The chemistry underlying its antioxidant properties

D Njus, PM Kelley, YJ Tu, HB Schlegel - Free Radical Biology and …, 2020 - Elsevier
Ascorbic acid (vitamin C) is an unusual antioxidant in that it donates a single reducing
equivalent, and the radical it forms, monodehydroascorbate, reacts preferentially with …

Natural oxidase-mimicking copper-organic frameworks for targeted identification of ascorbate in sensitive sweat sensing

Z Wang, Y Huang, K Xu, Y Zhong, C He, L Jiang… - Nature …, 2023 - nature.com
Sweat sensors play a significant role in personalized healthcare by dynamically monitoring
biochemical markers to detect individual physiological status. The specific response to the …

High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …

Chemical stability of ascorbic acid integrated into commercial products: A review on bioactivity and delivery technology

X Yin, K Chen, H Cheng, X Chen, S Feng, Y Song… - Antioxidants, 2022 - mdpi.com
The L-enantiomer of ascorbic acid is commonly known as vitamin C. It is an indispensable
nutrient and plays a key role in retaining the physiological process of humans and animals …

Ascorbate oxidation by iron, copper and reactive oxygen species: Review, model development, and derivation of key rate constants

J Shen, PT Griffiths, SJ Campbell, B Utinger… - Scientific reports, 2021 - nature.com
Ascorbic acid is among the most abundant antioxidants in the lung, where it likely plays a
key role in the mechanism by which particulate air pollution initiates a biological response …

[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

[HTML][HTML] Ascorbic acid metabolism and functions: A comparison of plants and mammals

N Smirnoff - Free Radical Biology and Medicine, 2018 - Elsevier
Ascorbic acid is synthesised by eukaryotes, the known exceptions being primates and some
other animal groups which have lost functional gulonolactone oxidase. Prokaryotes do not …

Magnetic field boosted ferroptosis-like cell death and responsive MRI using hybrid vesicles for cancer immunotherapy

B Yu, B Choi, W Li, DH Kim - Nature communications, 2020 - nature.com
We report a strategy to boost Fenton reaction triggered by an exogenous circularly polarized
magnetic field (MF) to enhance ferroptosis-like cell-death mediated immune response, as …

Two faces of vitamin C—antioxidative and pro-oxidative agent

J Kaźmierczak-Barańska, K Boguszewska… - Nutrients, 2020 - mdpi.com
Vitamin C has been known for decades. It is common in everyday use as an element of the
diet, supplementation, and a preservative. For years, research has been conducted to …