Probiotics and competitive exclusion of pathogens in shrimp aquaculture
Probiotics, live microorganisms that, when administered in adequate amounts, confer a
health benefit on the host, offer an alternative to antibiotics and have become popular …
health benefit on the host, offer an alternative to antibiotics and have become popular …
Root of the tree: the significance, evolution, and origins of the ribosome
The ribosome is an ancient molecular fossil that provides a telescope to the origins of life.
Made from RNA and protein, the ribosome translates mRNA to coded protein in all living …
Made from RNA and protein, the ribosome translates mRNA to coded protein in all living …
Spatial transcriptomics of planktonic and sessile bacterial populations at single-cell resolution
INTRODUCTION Microbial populations display heterogeneous gene expression profiles that
result in phenotypic differences between individual bacteria. This diversity can allow …
result in phenotypic differences between individual bacteria. This diversity can allow …
Parvimonas micra, Peptostreptococcus stomatis, Fusobacterium nucleatum and Akkermansia muciniphila as a four-bacteria biomarker panel of colorectal cancer
Dysbiosis of the gut microbiome has been associated with the pathogenesis of colorectal
cancer (CRC). We profiled the microbiome of gut mucosal tissues from 18 CRC patients and …
cancer (CRC). We profiled the microbiome of gut mucosal tissues from 18 CRC patients and …
Principles of cellular resource allocation revealed by condition-dependent proteome profiling
Growing cells coordinate protein translation with metabolic rates. Central to this coordination
is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins …
is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins …
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies
When conditions change, unicellular organisms rewire their metabolism to sustain cell
maintenance and cellular growth. Such rewiring may be understood as resource re …
maintenance and cellular growth. Such rewiring may be understood as resource re …
Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions
How innate T cells (ITC), including invariant natural killer T (iNKT) cells, mucosal-associated
invariant T (MAIT) cells, and γδ T cells, maintain a poised effector state has been unclear …
invariant T (MAIT) cells, and γδ T cells, maintain a poised effector state has been unclear …
Suboptimal resource allocation in changing environments constrains response and growth in bacteria
To respond to fluctuating conditions, microbes typically need to synthesize novel proteins.
As this synthesis relies on sufficient biosynthetic precursors, microbes must devise effective …
As this synthesis relies on sufficient biosynthetic precursors, microbes must devise effective …
Ribosome-binding antibiotics increase bacterial longevity and growth efficiency
Antibiotics, by definition, reduce bacterial growth rates in optimal culture conditions;
however, the real-world environments bacteria inhabit see rapid growth punctuated by …
however, the real-world environments bacteria inhabit see rapid growth punctuated by …
Bacterial inclusion bodies are industrially exploitable amyloids
Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …