The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …

Recent years have witnessed the expansion of tissue failures and diseases. The uprising of
regenerative medicine converges the sight onto stem cell-biomaterial based therapy. Tissue …

Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Background Human induced pluripotent stem cells (hiPSCs) hold enormous promise in
accelerating breakthroughs in understanding human development, drug screening, disease …

The routine application of human pluripotent stem cells (hPSCs) and their derivatives in
biomedicine and drug discovery will require the constant supply of high-quality cells by …

Articular cartilage defects are one of the major challenges in orthopedic and trauma surgery.
However, the poor ability of cartilage to self-repair has motivated efforts to engineer …

Cell therapeutics—using cells as living drugs—have made advances in many areas of
medicine. One of the most clinically studied cell-based therapy products is mesenchymal …

The ability to develop cost‐effective, scalable and robust bioprocesses for human pluripotent
stem cells (hPSCs) will be key to their commercial success as cell therapies and tools for …

Bioreactor‐based processes are the method of choice for efficient expansion of cells in a
controlled setting. However, induced pluripotent stem cells (iPSCs) have proven to be …

Cellular biomanufacturing technologies are a critical link to the successful application of cell
and scaffold based regenerative therapies, organs-on-chip devices, disease models and …