Two-component systems (TCS) comprising sensor histidine kinases and response regulator
proteins are among the most important players in bacterial and archaeal signal transduction …

Two-component systems reprogramme diverse aspects of microbial physiology in response
to environmental cues. Canonical systems are composed of a transmembrane sensor …

Abstract The MPI Bioinformatics Toolkit (http://toolkit. tuebingen. mpg. de) is an open,
interactive web service for comprehensive and collaborative protein bioinformatic analysis. It …

Motile Escherichia coli cells track gradients of attractant and repellent chemicals in their
environment with transmembrane chemoreceptor proteins. These receptors operate in …

Histidine kinases (HKs) are major players in bacterial signaling. There has been an
explosion of new HK crystal structures in the last 5 years. We globally analyze the structures …

α-Helical coiled coils were described more than 60 years ago as simple, repetitive structures
mediating oligomerization and mechanical stability. Over the past 20 years, however, they …

Increased expression of chromosomal genes for resistance-nodulation-cell division (RND)-
type efflux systems plays a major role in the multidrug resistance (MDR) of Acinetobacter …

Two-component signal transduction systems (TCSs) are widely conserved in bacteria to
respond to and adapt to the changing environment. Since TCSs are also involved in …

Context: Parkinson's disease (PD) is the second common progressive neurodegenerative
disease, distressing older men and is prevalent Worldwide. Objectives: This article is aimed …

INTRODUCTION Microorganisms obtain most of the information about their environments
through membrane-associated signaling systems. One of the most abundant classes of …