Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach

G Mahmoodi Chalbatani, H Dana… - International journal …, 2019 - Taylor & Francis
Cancer is one of the most complex diseases that has resulted in multiple genetic disorders
and cellular abnormalities. Globally, cancer is the most common health concern disease that …

The physiological functions and pharmaceutical applications of inulin: A review

X Wan, H Guo, Y Liang, C Zhou, Z Liu, K Li, F Niu… - Carbohydrate …, 2020 - Elsevier
Abstract Inulin (IN), a fructan-type plant polysaccharide, is widely found in nature. The major
plant sources of IN include chicory, Jerusalem artichoke, dahlia etc. Studies have found that …

[HTML][HTML] Inulin, a flexible oligosaccharide. II: Review of its pharmaceutical applications

MA Mensink, HW Frijlink… - Carbohydrate …, 2015 - Elsevier
Inulin is a flexible oligosaccharide which has been used primarily in food for decades.
Recently new applications in the pharmaceutical arena were described. In a previous review …

Natural microgranular cellulose as alternative catalyst to metal nanoparticles for H2 production from NaBH4 methanolysis

N Sahiner, S Demirci - Applied Catalysis B: Environmental, 2017 - Elsevier
Herein, we report the utilization of microgranular cellulose as a catalyst in virgin and in
modified form to be used as metal free catalyst directly in methanolysis reaction of NaBH 4 …

Polymeric nanoparticles for siRNA delivery: Production and applications

G Cavallaro, C Sardo, EF Craparo, B Porsio… - International journal of …, 2017 - Elsevier
Gene therapy through the use of siRNA and a polymeric carrier are becoming an efficient
therapeutic option to conventional pharmaceutical formulations for the treatment of deadly …

Inulin and its application in drug delivery

F Afinjuomo, S Abdella, SH Youssef, Y Song, S Garg - Pharmaceuticals, 2021 - mdpi.com
Inulin's unique and flexible structure, stabilization/protective effects, and organ targeting
ability make it an excellent drug delivery carrier compared to other biodegradable …

The landscape of nanoparticle-based siRNA delivery and therapeutic development

M Moazzam, M Zhang, A Hussain, X Yu, J Huang… - Molecular Therapy, 2024 - cell.com
Five small interfering RNA (siRNA)-based therapeutics have been approved by the Food
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …

Potential applications of hydrophobically modified inulin as an active ingredient in functional foods and drugs-A review

M Usman, C Zhang, PJ Patil, A Mehmood, X Li… - Carbohydrate …, 2021 - Elsevier
Over the past few years, hydrophobically modified inulin (HMI) has gained considerable
attention due to its multitudinous features. The targeted release of drugs remains a subject of …

Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies

M Farooq, S Sagbas, M Sahiner, M Siddiq, M Turk… - Carbohydrate …, 2017 - Elsevier
Gum Arabic (GA) microgels were successfully prepared via reverse micellization method
with high yield (78.5±5.0%) in 5–100 μm size range using divinyl sulfone (DVS) as a …

Synthesis of Schiff bases modified inulin derivatives for potential antifungal and antioxidant applications

Y Chen, Y Mi, Q Li, F Dong, Z Guo - International journal of biological …, 2020 - Elsevier
In this study, the structure of inulin was chemically modified by Schiff bases in order to
improve its biological activity. A total of 6 kinds of inulin derivatives were synthesized …