[HTML][HTML] Roles of oxidative stress in synaptic dysfunction and neuronal cell death in Alzheimer's disease

G Plascencia-Villa, G Perry - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …

Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta… - The …, 2017 - discovery.ucl.ac.uk
Acting now on dementia prevention, intervention, and care will vastly improve living and
dying for individuals with dementia and their families, and in doing so, will transform the …

Mild cognitive impairment

AM Sanford - Clinics in geriatric medicine, 2017 - geriatric.theclinics.com
Mild cognitive impairment (MCI), first fully characterized by Petersen and associates in 1997,
1 generally refers to impairment in cognition above that which is seen with normal age …

The Alzheimer's disease assessment scale–cognitive subscale (ADAS-Cog): modifications and responsiveness in pre-dementia populations. a narrative review

JK Kueper, M Speechley… - Journal of Alzheimer's …, 2018 - journals.sagepub.com
The Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-Cog) was
developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease …

The diagnosis and management of mild cognitive impairment: a clinical review

KM Langa, DA Levine - Jama, 2014 - jamanetwork.com
Importance Cognitive decline is a common and feared aspect of aging. Mild cognitive
impairment (MCI) is defined as the symptomatic predementia stage on the continuum of …

Mitochondria as potential targets in Alzheimer disease therapy: an update

G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Cognitive impairment in older adults: epidemiology, diagnosis, and treatment

NP Palmer, BT Ortega, P Joshi - Psychiatric Clinics, 2022 - psych.theclinics.com
With an increasingly aging population, health care providers will treat a higher number of
patients with cognitive impairment. Identifying cognitive impairment and intervening early …

Alzheimer's disease

C Ballard, S Gauthier, A Corbett, C Brayne, D Aarsland… - the Lancet, 2011 - thelancet.com
An estimated 24 million people worldwide have dementia, the majority of whom are thought
to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health …

Mechanism of oxidative stress and synapse dysfunction in the pathogenesis of Alzheimer's disease: understanding the therapeutics strategies

PK Kamat, A Kalani, S Rai, S Swarnkar, S Tota… - Molecular …, 2016 - Springer
Synapses are formed by interneuronal connections that permit a neuronal cell to pass an
electrical or chemical signal to another cell. This passage usually gets damaged or lost in …

What did you do yesterday? A meta-analysis of sex differences in episodic memory.

M Asperholm, N Högman, J Rafi, A Herlitz - Psychological bulletin, 2019 - psycnet.apa.org
To remember what one did yesterday is an example of an everyday episodic memory task,
in which a female advantage has sometimes been reported. Here, we quantify the impact of …