[HTML][HTML] Phenolic acids: Natural versatile molecules with promising therapeutic applications

N Kumar, N Goel - Biotechnology reports, 2019 - Elsevier
Plant phenolics are considered to be a vital human dietary component and exhibit a
tremendous antioxidant activity as well as other health benefits. Epidemiology evidence …

An update of Nrf2 activators and inhibitors in cancer prevention/promotion

F Pouremamali, A Pouremamali, M Dadashpour… - Cell Communication and …, 2022 - Springer
Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription
factor that defends against endogenous or exogenous stressors. By inducing several …

Combination therapy in combating cancer

RB Mokhtari, TS Homayouni, N Baluch… - …, 2017 - pmc.ncbi.nlm.nih.gov
Combination therapy, a treatment modality that combines two or more therapeutic agents, is
a cornerstone of cancer therapy. The amalgamation of anti-cancer drugs enhances efficacy …

Role of resveratrol in regulation of cellular defense systems against oxidative stress

VL Truong, M Jun, WS Jeong - Biofactors, 2018 - Wiley Online Library
Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and
their commercial products such as red wine. It has been demonstrated to exhibit a variety of …

Effect of resveratrol on markers of oxidative stress and sirtuin 1 in elderly adults with type 2 diabetes

BI García-Martínez, M Ruiz-Ramos… - International journal of …, 2023 - mdpi.com
Type 2 diabetes (T2D) affects a large part of the adult population and impairs its quality of
life. Because of this, natural compounds with antioxidant, anti-inflammatory and …

[HTML][HTML] Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

Y Mizunoe, M Kobayashi, Y Sudo, S Watanabe… - Redox biology, 2018 - Elsevier
Dysfunction of autophagy, which regulates cellular homeostasis by degrading organelles
and proteins, is associated with pathogenesis of various diseases such as cancer …

The anti-cancer effect of polyphenols against breast cancer and cancer stem cells: molecular mechanisms

A Abdal Dayem, HY Choi, GM Yang, K Kim, SK Saha… - Nutrients, 2016 - mdpi.com
The high incidence of breast cancer in developed and develo** countries, and its
correlation to cancer-related deaths, has prompted concerned scientists to discover novel …

Contribution of Nrf2 modulation to the mechanism of action of analgesic and anti-inflammatory drugs in pre-clinical and clinical stages

L Staurengo-Ferrari, S Badaro-Garcia… - Frontiers in …, 2019 - frontiersin.org
Despite the progress that has occurred in recent years in the development of therapies to
treat painful and inflammatory diseases, there is still a need for effective and potent …

Antioxidative stress mechanisms behind resveratrol: a multidimensional analysis

T Gu, N Wang, T Wu, Q Ge, L Chen - Journal of Food Quality, 2021 - Wiley Online Library
Over the past decade, oxidative stress was shown to be a key factor for various diseases.
The term “antioxidant” also rapidly gained attention worldwide, viewed as beneficial in …